N-Boc-1,3-propanediamine

N-Boc-1,3-propanediamine Basic information
Product Name:N-Boc-1,3-propanediamine
Synonyms:N-(3-Aminopropyl)carbamic acid tert-butyl ester ,85%;tert-butyl (3-aminopropyl)carbamate(SALTDATA: FREE);Propane-1,3-diamine, N-BOC protected;1,3-Diaminopropane, N-BOC protected, tert-Butyl (3-aminoprop-1-yl)carbamate;N-Boc-1,3-diaminopropane, tert-Butyl N-(3-aminopropyl)carbamate;tert-Butyl N-(3-aMinopropyl)ca;N-(TERT-BUTOXYCARBONYL)-1,3-DIAMINOPROPANE;N-(TERT-BUTOXYCARBONYL)-1,3-PROPANEDIAMINE
CAS:75178-96-0
MF:C8H18N2O2
MW:174.24
EINECS:628-600-3
Product Categories:Amines and Anilines;N-BOC;Monoprotected Diaminoalkanes;N-Boc-diaminoalkanes;Bifunctional Linkers;Building Blocks;Chemical Biology;Chemical Synthesis;Linkers and Crosslinkers;Nitrogen Compounds;Organic Building Blocks;Protected Amines;pharmacetical
Mol File:75178-96-0.mol
N-Boc-1,3-propanediamine Structure
N-Boc-1,3-propanediamine Chemical Properties
Melting point 22 °C (lit.)
Boiling point 203 °C (lit.)
density 0.998 g/mL at 20 °C (lit.)
refractive index n20/D 1.454(lit.)
Fp >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Miscible with methanol.
form Liquid
pka12.73±0.46(Predicted)
Specific Gravity0.998
color Colorless
Sensitive Air Sensitive
BRN 3588328
InChIKeyPOHWAQLZBIMPRN-UHFFFAOYSA-N
CAS DataBase Reference75178-96-0(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 22-34
Safety Statements 26-36/37/39-45
RIDADR UN 3259 8/PG 3
WGK Germany 3
10-34
Hazard Note Irritant
HazardClass 8
PackingGroup III
HS Code 29212900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
N-Boc-1,3-propanediamine Usage And Synthesis
Chemical PropertiesColorless to light yellow liquid
UsesN-Boc-1,3-diaminopropane is used in the preparation of spermidine analogues as well as in the preparation of pharmacologically active compounds. It is also used in suzuki reaction. Further, it is used in the preparation of [3-(3-cyano-propylamino)-propyl]-carbamic acid tert-butyl ester.
N-Boc-1,3-propanediamine Preparation Products And Raw materials
Raw materialsEthanol-->Sodium hydroxide-->Hydrochloric acid-->Methanol-->Dichloromethane-->Acetic acid-->Chloroform-->Di-tert-butyl dicarbonate-->Ethylenediamine-->1,3-Diaminopropane
Preparation ProductsBIS- BOC-SPERMIDINE
tert-Butyl N-(4-aminobutyl)carbamate BOC-ASP-OH t-butyl chloroformate 2,2-DIMETHYL-1,3-PROPANEDIAMINE Cyhalofop-butyl Chlorpropham POLYURETHANE BOC-L-Asparagine Buprofezin N-BOC-1,3-PROPANEDIAMINE HYDROCHLORIDE tert-Butyl 4-aminobenzoate butyl rubber tert-Butyl carbamate N-Boc-1,3-propanediamine 1-BENZYL-3-(TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE Tamoxifen tert-Butyl glycinate tert-Butyl carbazate

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