10,11-DIHYDROCARBAMAZEPINE

10,11-DIHYDROCARBAMAZEPINE Basic information
Product Name:10,11-DIHYDROCARBAMAZEPINE
Synonyms:f)azepine-5-carboxamide,10,11-dihydro-5h-dibenz(;10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE;10,11-DIHYDROCARBAMAZEPINE;10,11-Dihydro5H-dibenzo[b,f]azepine-5-carboxamide;10,11-Dihydrocarbamazepine,99%;5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide;10,11-Dihydrocarbamazepine,10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide;Carbamazepine Related Compound A (50 mg) (10,11-dihydrocarbamazepine)
CAS:3564-73-6
MF:C15H14N2O
MW:238.28
EINECS:222-649-0
Product Categories:Amines, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Amines;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:3564-73-6.mol
10,11-DIHYDROCARBAMAZEPINE Structure
10,11-DIHYDROCARBAMAZEPINE Chemical Properties
Melting point 205-210 °C(lit.)
Boiling point 394.5±52.0 °C(Predicted)
density 1.232±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility dichloromethane: soluble2.5%, clear, colorless
form neat
pka14.07±0.20(Predicted)
color White to Off-White
Water Solubility Soluble in dichloromethane. Insoluble in water.
BRN 196969
Safety Information
Hazard Codes Xn
Risk Statements 22-42/43
Safety Statements 22-24/25-45-36/37
WGK Germany 3
RTECS HN8300000
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
10,11-DIHYDROCARBAMAZEPINE Usage And Synthesis
Chemical Propertieswhite crystals or needles
UsesA dihydro impurity of Carbamazepine (C175840)
Uses10,11-Dihydrocarbamazepine is used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It can be used in chemiluminescence method for determination of carbamazepine.
General Description10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated.
10,11-DIHYDROCARBAMAZEPINE Preparation Products And Raw materials
N-Carbamoyl Carbamazepine R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN 10-HYDROXY-10,11-DIHYDROCARBAMAZEPINE rac trans-10,11-Dihydro-10,11-dihydroxy Carbamazepine Carbamazepine 10,11-Dihydro-10-hydroxycarbamazepine-d3 Carbamazepine-10,11-Epoxide-D2 trans-10,11-Dihydroxy-10,11-dihydrocarbamazepine 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE 10,11-DIHYDROCARBAMAZEPINE BIA 2-093 10,11-DIHYDRO-10-HYDROXY CARBAMAZEPINE-D4 CARBAMAZEPINE IMP. A (EP): 10,11-DIHYDRO-5H-DIBENZO[B,F]-AZEPINE-5-CARBOXAMIDE (10,11-DIHYDROCARBAMAZEPINE) CARBAMAZEPINE 10,11-EPOXIDE-13C,D2 OXCARBAZEPINE-D4 Oxcarbazepine S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN CARBAMAZEPINE-10,11-EPOXIDE-D10 (RINGS-D10)

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