ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Proline derivatives N-Boc-4-oxo-L-proline

N-Boc-4-oxo-L-proline

N-Boc-4-oxo-L-proline Basic information
Product Name:N-Boc-4-oxo-L-proline
Synonyms:N-Boc-4-oxo-L-proline;(Tert-Butoxy)Carbonyl 4-oxo-Pro-OH;Teneint-F(Tene-int-B);(2S)-N-Boc-4-oxo-L-proline;Boc-4-oxo-L-Pro;(2S)-N-Boc-4-Oxo-proline;(2S)-4-Oxopyrrolidine-2-carboxylic acid, N-BOC protected 97%;(2S)-1-(tert-Butoxycarbonyl)-4-oxo-2-pyrrolidinecarboxylic acid
CAS:84348-37-8
MF:C10H15NO5
MW:229.23
EINECS:617-556-0
Product Categories:Pharmaceuticalintermediates;pharmacetical
Mol File:84348-37-8.mol
N-Boc-4-oxo-L-proline Structure
N-Boc-4-oxo-L-proline Chemical Properties
Melting point 160 °C (dec.)
alpha 1 º (c=1 in chloroform)
Boiling point 390.8±42.0 °C(Predicted)
density 1.304±0.06 g/cm3(Predicted)
vapor pressure 0.001Pa at 25℃
storage temp. Inert atmosphere,2-8°C
form Solid:crystalline
pka3.85±0.20(Predicted)
color White to Almost white
optical activity[α]22/D +19.0 to +23.0°, c = 0.5 in acetone
Water Solubility Insoluble in water.
LogP0.49
CAS DataBase Reference84348-37-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-36
Safety Statements 26
WGK Germany 3
HS Code 29339900
MSDS Information
N-Boc-4-oxo-L-proline Usage And Synthesis
Chemical Propertieswhite to off-white solid
UsesN-Boc-4-oxo-L-proline is used in practical Synthesis of Boc-Protected cis-4-Trifluoromethyl and cis-4-Difluoromethyl-l- prolines.
DefinitionChEBI: Boc-L-Pro(4-oxo) is a proline derivative.
N-Boc-4-oxo-L-proline Preparation Products And Raw materials
Preparation ProductsBOC-4-OXO-PRO-OME-->BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER-->N-Boc-cis-4-Hydroxy-L-proline-->(2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester
N-Methyl-2-pyrrolidone D-Proline N-Vinyl-2-pyrrolidone BOC-L-Proline 4-OXO-PROLINE BOC-4-OXO-PRO-OME Polyvinylpyrrolidone Norvaline, 4-oxo- (9CI) L-Proline cis-4-Hydroxy-L-proline BOC-L-PRO(4-OXO)-O-BN Methyl 1-Methyl-2-oxopyrrolidine-3-carboxylate N-Boc-4-oxo-L-proline CARBOXYLIC ACID L-PROLINE-(4-3H(N)) Carbamic acid, (2-oxopropyl)-, 1,1-dimethylethyl ester (9CI) N-Boc-5-aminolevulinic acid Pyrrolidine
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