Dodecyltriphenylphosphonium bromide Usage And Synthesis
Description
Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2
Definition
ChEBI: An organic bromide salt that containing equal numbers of dodecyl(triphenyl)phosphonium cations and bromide anions.
References
References:
Dodecyltriphenylphosphonium bromide Preparation Products And Raw materials
