Methyl 3-hydroxythiophene-2-carboxylate

Methyl 3-hydroxythiophene-2-carboxylate Basic information

Product Name:	Methyl 3-hydroxythiophene-2-carboxylate
Synonyms:	METHYL 3-HYDROXYTHIOPHENE-2-CARBOXYLATE;METHYL-3-HYDROXYTHIOPHENE CARBOXYLATE;METHYL 3-HYDROXY-2-THIOPHENECARBOXYLATE;3-HYDROXYTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER;Methyl 3-hydroxythiophene-2-carboxylate ,97%;3-hydro-2-thiophenca;3-Hydroxy-2-(methoxycarbonyl)thiophene;3-Hydroxy-2-thiophenecarboxylic acid Methyl ester
CAS:	5118-06-9
MF:	C6H6O3S
MW:	158.18
EINECS:	692-439-5
Product Categories:	Thiophenes & Benzothiophenes;Building Blocks;Esters;Thiophenes & Benzothiophenes;Heterocyclic Building Blocks;Thiophenes
Mol File:	5118-06-9.mol

Methyl 3-hydroxythiophene-2-carboxylate Chemical Properties

Melting point	38-43 °C(lit.)
Boiling point	107-109°C 13mm
density	1.372±0.06 g/cm3(Predicted)
Fp	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	9.47±0.10(Predicted)
form	powder to crystal
color	White to Orange to Green
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	5118-06-9(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

Methyl 3-hydroxythiophene-2-carboxylate Usage And Synthesis

Uses	3-Hydroxy-2-thiophenecarboxylic Acid Methyl Ester, is used as a reactant in synthesizing nitro-products where reaction occurs with thiophenol.
Chemical Properties	white to light yellow crystal powder
Uses	Methyl 3-hydroxythiophene-2-carboxylate is used in medicine.
Synthesis Reference(s)	Synthetic Communications, 9, p. 731, 1979 DOI: 10.1080/00397917908064186

Methyl 3-hydroxythiophene-2-carboxylate Preparation Products And Raw materials

Raw materials	Hydrochloric acid-->Ethyl acetate-->Methanol-->Dichloromethane-->Sodium-->Magnesium sulfate-->Hexane-->Magnesium-->Methyl thioglycolate-->Ethyl propiolate-->METHYL ALPHA-CHLOROACRYLATE-->ETHYL ALPHA-CHLOROACRYLATE-->BOC-3-AMINO-THIOPHENE-2-CARBOXYLIC ACID-->METHYL 3-METHOXYACRYLATE-->METHYL 3-OXOTETRAHYDROTHIOPHENE-2-CARBOXYLATE-->Methyl propiolate
Preparation Products	Tenoxicam-->2-Thiophenecarboxylicacid,3-hydroxy-4-nitro-,methylester(7CI,9CI)-->2-Thiophenecarboxylic acid, 2-chloro-2,3-dihydro-3-oxo-, Methyl ester

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