ChemicalBook Product Catalog Biochemical Engineering Inhibitors Apoptosis Caspase activator Tasisulam

Tasisulam

Tasisulam Basic information
Product Name:Tasisulam
Synonyms:Benzamide, N-((5-bromo-2-thienyl)sulfonyl)-2,4-dichloro-;Ly573636;Ly-573636;TS81557;LY573636 (TasisulaM);Tasisulam(Ly-573636;N-(2,4-Dichlorobenzoyl)-5-bromothiophene-2-sulfonamide LY573636 Tasisulam;Tasisulam N-(2,4-Dichlorobenzoyl)-5-bromothiophene-2-sulfonamide
CAS:519055-62-0
MF:C11H6BrCl2NO3S2
MW:415.11
EINECS:
Product Categories:Inhibitors
Mol File:519055-62-0.mol
Tasisulam Structure
Tasisulam Chemical Properties
density 1.812
storage temp. Store at -20° C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form A crystalline solid
pka3.45±0.10(Predicted)
Safety Information
MSDS Information
Tasisulam Usage And Synthesis
UsesThe sodium salt of Tasisulam has potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial-targeted mechanism involving the loss of mitochondrial membrane potential and induction of reactive oxygen species (ROS).
Tasisulam Preparation Products And Raw materials
Olaparib AZD-9291 CRA-02478 Ibrutinib tasquinimod CX-4945 GDC-0032 PAC1 Tazemetostat (EPZ-6438) 3-Aminobenzenesulfonamide Cyclopropanesulfonamide Methanesulfonamide Benzenesulfonamide Sulfanilamide Tasisulam p-Toluenesulfonamide 5-Bromothiophene-2-sulfonamide
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