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| | 2-Carboxybenzaldehyde Basic information |
| | 2-Carboxybenzaldehyde Chemical Properties |
| Melting point | 94-96 °C(lit.) | | Boiling point | 231.65°C (rough estimate) | | density | 1,404 g/cm3 | | refractive index | 1.4500 (estimate) | | Fp | 198°(388°F) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Crystalline Powder | | pka | 4.57±0.10(Predicted) | | color | White to slightly beige | | PH | 2 (20g/l, H2O, 20℃) | | Water Solubility | soluble | | Sensitive | Air Sensitive | | BRN | 742381 | | Stability: | Hygroscopic | | InChIKey | DYNFCHNNOHNJFG-UHFFFAOYSA-N | | CAS DataBase Reference | 119-67-5(CAS DataBase Reference) | | EPA Substance Registry System | Benzoic acid, 2-formyl- (119-67-5) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-20/21/22 | | Safety Statements | 26-36-24/25 | | RIDADR | PG2 | | WGK Germany | 2 | | RTECS | TH7015000 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29183000 | | Toxicity | mouse,LD50,oral,4480mg/kg (4480mg/kg),Journal of Antibiotics. Vol. 27, Pg. 665, 1974. |
| | 2-Carboxybenzaldehyde Usage And Synthesis |
| Chemical Properties | white to slightly beige crystalline powder | | Uses | 2-Carboxybenzaldehyde is a carboxylated derivative of benzaldehyde which is readily converted to 2-hydroxymethyl benzoic acid by CBA dehydrogenase. 2-Carboxybenzaldehyde is a metabolite of ampicillin phthalidyl ester. It has been used to synthesize a series of N-substituted isoindolinones by reductive C-N coupling and intramolecular amidation with amines. | | Uses | 2-Carboxybenzaldehyde is a carboxylated derivative of benzaldehyde which is readily converted to 2-hydroxymethyl benzoic acid by CBA dehydrogenase. 2-Carboxybenzaldehyde is a metabolite of ampicillin
phthalidyl ester. | | Definition | ChEBI: An aldehydic acid which consists of benzoic acid substituted by a formyl group at position 2. | | Synthesis Reference(s) | Tetrahedron Letters, 14, p. 3535, 1973 DOI: 10.1016/S0040-4039(01)86963-X
The Journal of Organic Chemistry, 32, p. 3200, 1967 DOI: 10.1021/jo01285a061 |
| | 2-Carboxybenzaldehyde Preparation Products And Raw materials |
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