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| N-Chlorosuccinimide Basic information |
| N-Chlorosuccinimide Chemical Properties |
Melting point | 148-150 °C (lit.) | density | 1,65 g/cm3 | vapor pressure | 1.04Pa at 25℃ | refractive index | 1.4378 (estimate) | Fp | >110°C | storage temp. | Store at +2°C to +8°C. | solubility | 14g/l | pka | -2.78±0.20(Predicted) | form | Crystalline Powder | color | White | Odor | chlorine odor | Water Solubility | Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether. | Sensitive | Moisture Sensitive | Merck | 14,2164 | Boiling point | 216.5°C | BRN | 113915 | InChIKey | JRNVZBWKYDBUCA-UHFFFAOYSA-N | LogP | -1.19 | CAS DataBase Reference | 128-09-6(CAS DataBase Reference) | NIST Chemistry Reference | N-Chlorosuccinimide(128-09-6) | EPA Substance Registry System | N-Chlorosuccinimide (128-09-6) |
| N-Chlorosuccinimide Usage And Synthesis |
Chemical Properties | white crystalline powder | Uses | N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes. | Uses | N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity. N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate. | Definition | ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide. | Flammability and Explosibility | Nonflammable |
| N-Chlorosuccinimide Preparation Products And Raw materials |
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