Isofraxidin

Isofraxidin Basic information

Product Name:	Isofraxidin
Synonyms:	7-hydroxy-6,8-dimethoxy-2h-1-benzopyran-2-on;7-hydroxy-6,8-dimethoxy-2h-1-benzopyran-2-one;7-hydroxy-6,8-dimethoxy-coumari;phytodolor;ISOFRAXIDIN;ISOFRAXIDINE;AKOS 243-93;6,8-DIMETHOXY-7-HYDROXYCOUMARIN
CAS:	486-21-5
MF:	C11H10O5
MW:	222.19
EINECS:
Product Categories:	Coumarins
Mol File:	486-21-5.mol

Isofraxidin Chemical Properties

Melting point	145～147℃
Boiling point	452.1±45.0 °C(Predicted)
density	1.358±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 250 mg/mL (1125.16 mM)
pka	7.92±0.20(Predicted)
form	neat
BRN	202652
CAS DataBase Reference	486-21-5(CAS DataBase Reference)

Safety Information

Safety Statements	24/25
WGK Germany	3
HS Code	29322090

MSDS Information

Isofraxidin Usage And Synthesis

Uses	Isofraxidin is used as an anti-inflammatory compound. Inhibits pro-inflammatory cytokines.
Definition	ChEBI: Isofraxidin is a hydroxycoumarin.

Isofraxidin Preparation Products And Raw materials

Raw materials	2H-1-Benzopyran-3-carboxylic acid, 7-hydroxy-6,8-dimethoxy-2-oxo--->Benzaldehyde, 2,4-dihydroxy-3,5-dimethoxy--->7,8-DIHYDROXY-6-METHOXYCOUMARIN-->3,5-DIBROMO-2,4-DIHYDROXYBENZALDEHYDE
Preparation Products	Indole-3-carboxaldehyde

Nicotinic acid Schisandrin A Diphenyldimethoxysilane DAPHNETIN Dimethyldimethoxysilane Tetrahydro-4H-pyran-4-one 8-METHOXYCOUMARIN 7,8-METHYLENEDIOXY-6-METHOXYCOUMARIN 6,7,8-TRIMETHOXYCOUMARIN Verapamil 1,1-Dimethoxyethane Isofraxidin 4'-Hydroxyacetophenone THYROGLOBULIN, HUMAN FRAXIN 7,8-DIHYDROXY-6-METHOXYCOUMARIN CHLOROPHOSPHONAZO III Isofraxidin-7-O-β-D-glucoside

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