artemisic acid

artemisic acid Basic information
Product Name:artemisic acid
Synonyms:artemisic acid;Artimisinic Acid;2-[[(1R)-4β,7-Dimethyl-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalen]-1α-yl]acrylic acid;Qing Hau acid;Qinghao acid;1-Naphthaleneaceticacid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-a-methylene-, (1R,4R,4aS,8aR)-;ARTEMISININIC ACID;4,11(13)-AMorphadien-12-oic acid
CAS:80286-58-4
MF:C15H22O2
MW:234.33
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;Miscellaneous Natural Products;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:80286-58-4.mol
artemisic acid Structure
artemisic acid Chemical Properties
Melting point 129-131℃
Boiling point 373.6±11.0 °C(Predicted)
density 1.019
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.32±0.11(Predicted)
form Solid
color White to Pale Yellow
LogP5.086 (est)
Safety Information
MSDS Information
artemisic acid Usage And Synthesis
UsesArtemisic Acid is a derivative of Artemisinin (A777500), an antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.
DefinitionChEBI: A monocarboxylic acid that is prop-2-enoic acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). I is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua.
artemisic acid Preparation Products And Raw materials
Raw materialsAmorphadiene-->Artemisinic Alcohol Impurity-->Ethanol-->D(+)-Glucose
Artesunate Artemether artemisic acid cis-1,2-divinylcyclohexane Artemisinin-d3 Dihydro ArteMisinin-13C,d4 Arteannuin H Deoxy Artemisinin Atemisinic Aldehyde Impurity Artemisinic Acid Carbonate Impurity Artemisinin Impurity 6 (11S)-Dihydroartemisinic Aldehyde Diketo aldehyde iMpurity of dihydroarteMisinin DHQHS 2 Artemisinic Alcohol Impurity Artemisinin (3aS,4R,6aS,7R,10R,10aR)-Octahydro-4,7-diMethyl-2H,10H-furo[3,2-i][2]benzopyran-8,10-diol 10-Acetate Artemisinin impurity 2

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