Columbin

Columbin Basic information
Product Name:Columbin
Synonyms:(1s,2s,3s,5s,8r,11r,12s)-5-(3-furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;Columbin, 98%, from limacia sagittata;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione;Tinosporin;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;1,4-Etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R,4R,4aR,6aR,9S,10aS,10bS)-
CAS:546-97-4
MF:C20H22O6
MW:358.39
EINECS:
Product Categories:Miscellaneous Natural Products
Mol File:546-97-4.mol
Columbin Structure
Columbin Chemical Properties
Melting point 190-191℃
alpha D +52.5° (pyridine)
Boiling point 410.82°C (rough estimate)
density 1.36
refractive index 1.4450 (estimate)
storage temp. -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.03 mg/ml
pka12.14±0.70(Predicted)
form Cryst.
Safety Information
WGK Germany 3
HS Code 29322090
MSDS Information
Columbin Usage And Synthesis
UsesColumbin is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species and is used in Asian and African folk medicine for analgesic and antipyretic properties.
DefinitionChEBI: Columbin is an organic heterotricyclic compound and an organooxygen compound.
Columbin Preparation Products And Raw materials
Preparation ProductsISOCOLUMBIN
dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate 10-Deacetylbaccatin III siegesmethyethericacid DARUTOSIDE Carboxyatractyloside β-Elemonic Acid 12-O-Tiglylphorbol-13 -isobutyrate (S)-(-)-2-Hydroxy-3,3-dimethylbutyric acid 2H-PYRAN-2-ONE, 3-ETHYLTETRAHYDRO-, (R)- Isopropyl-cyclohexanecarboxylic acid 2-PROPENYL 3,5,5-TRIMETHYLHEXANOATE METHYL TRANS-4-HYDROXYMETHYLCYCLOHEXANECARBOXYLATE ISOBUTYL VINYLACETATE Columbin ALLYLCYCLOHEXANE ACETATE tetrahydro-3-pentyl-2H-pyran-2-one (S)-(+)-HEXAHYDROMANDELIC ACID (CIS)-8-METHYLNON-6-ENOIC ACID

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