phospholipase C type I*from C perfringens;phospholipase C type iii from B. cereus;phospholipase C type ix*from C perfringens;phospholipase C type V from B. cereus;phospholipase C type xiv from*C. perfringens;PHOSPHOLIPASE C FROM CLOSTRIDIUM PER- &;PHOSPHOLIPASE C, PHOSPHATIDYLINOSITOL-*S PECIFIC FRO;PHOSPHOLIPASE C FROM CLOSTRIDIUM PER- FRINGENS, ~4 U/MG*
Phospholipase C (PLC) has been used to study adrenoceptor-mediated transmembrane signaling. It is also used to degrade inositol-containing phospholipids. Furthermore, it has been used to study 9E3 gene activation.
Uses
Phospholipase C from Clostridium perfringens has been used as a positive control in sandwich enzyme linked immunosorbent assay (ELISA) and ELISA.
Uses
The enzyme from Sigma has been used in the digestion of phosphatidylserine fraction of Schistosoma mansoni adult worms.
General Description
This product has been enhanced for energy efficiency and waste prevention when used in biodiesel research.
Biochem/physiol Actions
PLC hydrolyzes the phosphate bond on phosphatidylcholine and other glycerophospholipids yielding diacylglycerol. This enzyme also hydrolyzes the phosphate bonds of sphingomyelin, cardiolipin, choline plasmalogen and ceramide phospholipids. Phospholipase C is induced by thrombin and platelet-activating factor, forming 1,2-diacylglycerol and phosphatidic acid.
