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| | Cyclophosphamide-d4 Basic information |
| | Cyclophosphamide-d4 Chemical Properties |
| Melting point | 41-450C | | storage temp. | -20°C Freezer | | solubility | Chloroform: Slightly Soluble,Methanol: Slightly Soluble | | form | A solid |
| | Cyclophosphamide-d4 Usage And Synthesis |
| Description | Cyclophosphamide-d4 contains four deuterium atoms. It is intended for use as an internal standard for the quantification of cyclophosphamide by GC- or LC-MS. Cyclophosphamide is a nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders. In cells with low levels of aldehyde dehydrogenase, cyclophosphamide acts as a prodrug and is metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death. | | Chemical Properties | White to Off-White Solid | | Uses | Cyclophosphamide-d4 is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. Cyclophosphamide-d4 cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.
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| | Cyclophosphamide-d4 Preparation Products And Raw materials |
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