Asiaticoside

Asiaticoside Basic information
Product Name:Asiaticoside
Synonyms:ranosyl-(1-4)-o-beta-d-glucopyranosyl-(1-6)-o-beta-d-glucopyranosylester;CENTELASE;ASIATICOSIDE;MADECASOL;[6-[[3,4-Dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyl-oxan-2-yl)oxy-oxan-2-yl]oxymethyl]-3,4,5-trihydroxy-oxan-2-yl] (1S,2R,4aS,6aS,6bR,9S,10R,11R,12aS,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate;Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-.alpha.-L-mannopyranosyl-(1?4)-O-.beta.-D-glucopyranosyl-(1?6)-.beta.-D-glucopyranosyl ester, (2.alpha.,3.beta.,4.alpha.)-;ASIATICOSIDE(P);Gotu Kola (Centella Asiatica) (40%Asiatisides)
CAS:16830-15-2
MF:C48H78O19
MW:959.12
EINECS:240-851-7
Product Categories:Inhibitors;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Saponins;Alkaloids;Natural Plant Extract;The group of Asiaticoside
Mol File:16830-15-2.mol
Asiaticoside Structure
Asiaticoside Chemical Properties
Melting point 235-238°C
alpha D20 -14° (alc)
Boiling point 1017.5±65.0 °C(Predicted)
density 1.44±0.1 g/cm3(Predicted)
vapor pressure 0.001Pa at 160℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly)
pka12.50±0.70(Predicted)
form neat
color Crystals
Water Solubility 99mg/L
InChIKeyWYQVAPGDARQUBT-KRQXBQLUNA-N
LogP0.44 at 22℃
CAS DataBase Reference16830-15-2(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
RTECS YU9625000
1-10
HS Code 29389090
Asiaticoside Usage And Synthesis
DescriptionAsiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat a variety of ailments including dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. In various wound healing models, topical application (0.2-0.4%), injection (1 mg), or ingestion (1 mg/kg) of asiaticoside has been shown to increase hydroxyproline content, improve tensile strength, increase collagen synthesis and remodeling of the collagen matrix, promote epithelialization, stimulate glycosaminoglycan synthesis, and elevate antioxidant levels.
Chemical PropertiesWhite powder
UsesAsiatic Acid is a terpenoid saponin component isolated from Centella asiatica with antioxidant and anti-inflammatory activities. Asiaticoside has been shown to possess strong wound-healing properties and reduces scar formation.
Useswound healing, anxiolytic
DefinitionChEBI: Asiaticoside is a triterpenoid saponin.
Flammability and ExplosibilityNotclassified
Safety ProfileQuestionable carcinogen withexperimental tumorigenic data. When heated todecomposition it emits acrid smoke and fumes. Promoteshealing of wounds.
storage+4°C
Asiaticoside Preparation Products And Raw materials
Raw materialsPETROLEUM ETHER
Centella asiatica whole plant Sophoricoside Methyl ASIATICOSIDE(RG) aggreceride A PROPYLENEGLYCOLISOSTEARATE 1-OXODODECYL-D-GLUCOPYRANOSIDE 2-MONOSTEARIN 2,3-Dihydroxypropyl 14-methylpentadecanoate GLYCEROL MONOISOSTEARATE ASIATICOSIDE(SH) 1-OCTANOYL-BETA-D-GLUCOPYRANOSIDE Asiaticoside cp2000 Kresoxim-methyl Thiophanate-methyl Hydroxy asiaticoside METSULFURON METHYL 1-OXODODECYL-BETA-D-GLUCOPYRANOSIDE, 99+% Madecassol

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