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| | Nattokinase Basic information |
| Product Name: | Nattokinase | | Synonyms: | Nattokinase;Nattoesse Haruno-Ogawa;4-(carboxymethyl)-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic;Liposomal NATTOKINASE, NATTOKINASE NanoEmulsion, NanoActive NATTOKINASE, Oil-Soluble NATTOKINASE;4-(carboxymethyl)-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid;4-(Carboxymethyl)-2-[(1R)-1-{[N-(2,5-dichlorobenzoyl)glycyl]amino}-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid;Nattokinase (peptidolytic);NattoLife | | CAS: | 133876-92-3 | | MF: | C20H23BCl2N2O9 | | MW: | 517.12162 | | EINECS: | 229-880-6 | | Product Categories: | 133876-92-3 | | Mol File: | 133876-92-3.mol |  |
| | Nattokinase Chemical Properties |
| InChIKey | YTXSYWAKVMZICI-VVSYKVCONA-N | | SMILES | O1C(=O)CC(CC(O)=O)(C(O)=O)OB1[C@@H](NC(CNC(=O)C1=CC(Cl)=CC=C1Cl)=O)CC(C)C |&1:14,r| |
| | Nattokinase Usage And Synthesis |
| Chemical Properties | Nattokinase is an enzyme (a protein that speeds up biochemical reactions) that is extracted from a popular Japanese food called natto. Natto is boiled soybeans that have been fermented with a bacterium called Bacillus natto. | | Uses | Although nattokinase is promoted for use as a fibrinolytic and thrombolytic agent, clinical trials are lacking to support such use. There is also no substantial evidence that nattokinase lowers blood pressure in hypertension. | | Mechanism of action | Nattokinase decreases the ability of blood to clot. This "thins the blood" and might protect against conditions caused by blood clots such as stroke, heart attack, and others. | | Side effects | Small, short-term trials evaluating nattokinase reported no adverse reactions. There is a theoretical risk of bleeding, based on a case report of acute cerebellar hemorrhage in a patient with a history of ischemic stroke. Thrombosis was reported after substitution of nattokinase for warfarin in a patient with a mechanical aortic valve. Rare cases of late-onset anaphylaxis with natto have been attributed to poly-gamma-glutamic acid, a product of the fermentation process that may be present in nattokinase supplements. |
| | Nattokinase Preparation Products And Raw materials |
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