O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Basic information
Product Name:O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
Synonyms:O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine;3,5-Diiodo-L-tyrosinedihydrae;(S)-α-Amino-4-[(4-hydroxy-3-iodophenyl)oxy]-3-iodobenzenepropanoic acid;3-Iodo-O-(4-hydroxy-3-iodophenyl)-L-tyrosine;O-(3-Iodo-4-hydroxyphenyl)-3-iodo-L-tyrosine;3,3'-Diiodo-L-thyronine;(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid;(2S)-2-amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propionic acid
CAS:4604-41-5
MF:C15H13I2NO4
MW:525.08
EINECS:225-005-7
Product Categories:Amino Acids & Derivatives;Labeling and Diagnostics Reagents
Mol File:4604-41-5.mol
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Structure
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Chemical Properties
Melting point 178-180°C
Boiling point 520.7±50.0 °C(Predicted)
density 2.095±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility Aqueous Base (Slightly)
form Solid
pka2.17±0.20(Predicted)
color Off-White to Beige
Stability:Light Sensitive
Safety Information
WGK Germany 3
MSDS Information
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Usage And Synthesis
Description3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.
Chemical PropertiesOff-White Powder
UsesOf interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.
DefinitionChEBI: 3,3'-diiodo-L-thyronine is a 3,3'-diiodothyronine. It has a role as a human metabolite.
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Preparation Products And Raw materials
3,5-Diiodo-L-thyronine Levothyroxine EP Impurity A Thyroxine-4-hydroxy-3,5-diiodophenyl Ether DISCONTINUED 4-(4-Hydroxyphenoxy)-3,5-diiodo-benzaldehyde 3,5-DIIODO-4'-(4-HYDROXYPHENOXY)BENZOIC ACID TRIIODOTHYRONINE, L-3,5,3'-[125I]- Liothyronine sodium BOC-L-THYROXINE [125I]TRIIODOTHYRONINE Levothyroxine sodium THYROXINE, L-[125I]- L-[3',5'-125I]THYROXINE L-Thyroxine REVERSE T3 3,3',5, [125I]- O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine T3, N-SUCCINYL Sodium levothyroxine FMOC-L-THYROXINE

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