1-Chloro-2-propanol

1-Chloro-2-propanol Basic information

Product Name:	1-Chloro-2-propanol
Synonyms:	PROPYLENE CHLOROHYDRIN;PROPYLENE CHLOROHYDRINE;PROPYLENE CHLOROHYDRIN (SEC);SEC-PROPYLENE CHLOROHYDRIN;1-Chloro-2-propanol, remainder 2-chloro-1-propanol;(±)-1-chloro-propan-2-ol;1-Chloro-2-hydroxypropane;1-chloro-2-propano
CAS:	127-00-4
MF:	C3H7ClO
MW:	94.54
EINECS:	204-819-6
Product Categories:	API Intermediate;Analytical/Chromatography;Applications;Building Blocks;C2 to C6;Chemical Synthesis;Organics;Food Safety Testing;Processing and Packaging Contaminants;Alcohols;Chloropropanols;Organic Building Blocks;Oxygen Compounds
Mol File:	127-00-4.mol

1-Chloro-2-propanol Chemical Properties

Boiling point	126-127 °C(lit.)
density	1.111 g/mL at 25 °C(lit.)
refractive index	n20/D 1.439(lit.)
Fp	125 °F
storage temp.	Flammables area
Water Solubility	Soluble in water
solubility	Chloroform (Soluble), Methanol (Slightly)
form	clear liquid
pka	14.09±0.20(Predicted)
color	Colorless to Light yellow
Merck	14,7851
BRN	773653
Exposure limits	ACGIH: TWA 1 ppm (Skin)
Stability:	Stable. Flammable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	127-00-4(CAS DataBase Reference)
EPA Substance Registry System	1-Chloro-2-propanol (127-00-4)

Safety Information

Hazard Codes	Xn
Risk Statements	10-20-36/37/38
Safety Statements	26-36/39
RIDADR	UN 2611 6.1/PG 2
WGK Germany	3
RTECS	UA8942000
F	19
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	29055900
Hazardous Substances Data	127-00-4(Hazardous Substances Data)

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

1-Chloro-2-propanol Usage And Synthesis

Chemical Properties	colourless to light yellow liquid
Uses	1-Chloro-2-propanol has been used as: chemical intermediate for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol as α,β-halohydrin standard during the enzymatic synthesis of α,β-halohydrins from gaseous alkenes
Definition	ChEBI: 1-chloropropan-2-ol is a secondary alcohol that is isopropanol in which one of the methyl hydrogen atoms is substituted by chlorine. It is an organochlorine compound and a secondary alcohol. It derives from a hydride of a propane.
General Description	Clear colorless to light amber liquid with a mild non residual odor.
Air & Water Reactions	Soluble in water.
Reactivity Profile	May be sensitive to prolonged exposure to light. Incompatible with strong oxidizing agents.
Fire Hazard	1-Chloro-2-propanol is combustible.

1-Chloro-2-propanol Preparation Products And Raw materials

Raw materials	Hydrochloric acid-->Ethyl acetate-->Methanol-->Sodium borohydride-->Allyl chloride-->N,N-Dimethylacetamide-->Chloroacetone-->hypochlorous acid
Preparation Products	Propylene glycol-->1,1-Diphenylacetone-->METHACHOLINE CHLORIDE-->2-Chloro-1-propanol-->1,3-Dichloropropane-->1-(4-METHYLPHENOXY)-2-PROPANOL-->N-(2-HYDROXYPROPYL)MORPHOLINE-->(S)-1-Chloro-2-propanol-->1-DIETHYLAMINO-2-PROPANOL-->(R)-1-Chloro-2-propanol-->3-HYDROXYBUTYRONITRILE

ALPHA-(CHLOROMETHYL)-2,4-DICHLOROBENZYL ALCOHOL Chlorobutanol 2-(CHLOROMETHYL)TETRAHYDROPYRAN TRICHLORO PYRUVIC ACID 5-CHLOROMETHYL-2-OXAZOLIDINONE 2-CHLOROCYCLOHEXANOL (+)-CAMPHANIC ACID CHLORIDE 2,2,2-TRICHLORO-1,1-DIMETHYLETHYL CHLOROFORMATE 1,2,3,4-Tetrachloro-5,5-dimethoxycyclopentadiene Tetrahydrofurfuryl chloride 1-Chloro-2-propanol 2-Acetoxy-2-phenylacetyl chloride 3-Chloro-1,2-propanediol 2,2,2-Trichloro-1-phenylethyl acetate Epichlorohydrin 3-CHLORO-4-HYDROXYTETRAHYDROTHIOPHENE-1,1-DIOXIDE 1,3-DICHLORO-2-PROPANOL 2,2,6,6-TETRACHLOROCYCLOHEXANOL

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