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| | 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Basic information |
| Product Name: | 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE | | Synonyms: | 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE;4-Chloro-5H-pyrrol[3,2-d] pyrimidine;5H-Pyrrolo3,2-dpyrimidine, 4-chloro-;4-chloro-5H-pyrrolo[2,3-c]pyridine;4-Chloro-5H-pyrrolo[3,2-d...;6-chloro-9-deaza-7H-purine, 4-chloro-3H,5H-pyrrolo[3,2-d]pyriMidine, 4-Chloropyrrolo<3,2-d>pyriMidine;4-chloro-1H-pyrrolo[3,2-d]pyriMidine;6-chloro-9-deaza-7H-puri | | CAS: | 84905-80-6 | | MF: | C6H4ClN3 | | MW: | 153.57 | | EINECS: | 632-937-1 | | Product Categories: | Heterocycle-Pyrimidine series;CHIRAL CHEMICALS;Heterocycles series | | Mol File: | 84905-80-6.mol | ![4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Structure](CAS/GIF/84905-80-6.gif) |
| | 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Chemical Properties |
| Melting point | 186-188 °C (decomp)(Solv: water (7732-18-5); ethanol (64-17-5)) | | Boiling point | 325.9±22.0 °C(Predicted) | | density | 1.531±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 11.58±0.40(Predicted) | | form | solid | | color | Off-white |
| HazardClass | IRRITANT | | HS Code | 2933599590 |
| | 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Usage And Synthesis |
| Description | 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a purine analog that inhibits the growth of bacteria by binding to the enzyme DNA gyrase. It has been shown to be effective against staphylococcus and Mycobacterium tuberculosis. | | Uses | 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a chlorinated pyrrolopyrimidine used in the preparation of compounds with antibacterial and antitumor activities. | | Application | 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine binds to the enzyme DNA gyrase and prevents it from breaking down the bacterial DNA. This drug also has antimycobacterial activity due to its ability to bind to the enzyme RNA polymerase. |
| | 4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Preparation Products And Raw materials |
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