O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE

O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE Basic information
Product Name:O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
Synonyms:O-(tert-Butyl)hydroxylamine hydrochloride 98%;O-T-BUTYLHYDROXYLAMINE HYDROCHLORIDE;O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE;O-Tert-ButylhydroxylamineHCl;2-Aminooxy-2-methylpropane hydrochloride;O-(1,1-Dimethylethyl)hydroxylamine hydrochloride;tert-Butoxyamine hydrochloride;HydroxylaMine,O-(1,1-diMethylethyl)-, hydrochloride (1:1)
CAS:39684-28-1
MF:C4H12ClNO
MW:125.6
EINECS:254-590-1
Product Categories:Building Blocks;Chemical Synthesis;Hydroxylamines;Nitrogen Compounds;Nitrogen Compounds;Organic Building Blocks;Organic Building Blocks
Mol File:39684-28-1.mol
O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE Structure
O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE Chemical Properties
Melting point 158-159 °C(lit.)
storage temp. Inert atmosphere,Room Temperature
solubility H2O: soluble0.5g/10 mL
form powder to crystal
color White to Almost white
BRN 3668106
Safety Information
Hazard Codes F
Risk Statements 11
RIDADR UN 1325 4.1/PG 3
WGK Germany 3
10
HazardClass 4.1
PackingGroup 
HS Code 29280090
MSDS Information
ProviderLanguage
SigmaAldrich English
O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE Usage And Synthesis
Chemical PropertiesWhite crystalline powder
UsesReactant involved in synthesis of biologically active molecules including:• ;CGS 25966 derivatives for use as MMP inhibitors1• ;Imidazolidinedione derivatives for use as antimalarial treatments2• ;Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists3• ;Rab proteins for isoprenylation and geranylgeranylation inhibition4Reactant involved in:• ;Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents5• ;Double allylic alkylation of indole-2-hydroxamates6• ;SN2 substitution reactions at amide nitrogens7• ;Photoc
UsesO-tert-Butylhydroxylamine Hydrochloride is an reactant used in various synthesis of biologically active molecules such as camptothecin derivatives that exerts anti-tumor activity, oxime derivatives as GPR119 agonists and their preparation and highly Potent Matrix Metalloproteinase Inhibitors.
UsesReactant involved in synthesis of biologically active molecules including:
  • CGS 25966 derivatives for use as MMP inhibitors
  • Imidazolidinedione derivatives for use as antimalarial treatments
  • Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists
  • Rab proteins for isoprenylation and geranylgeranylation inhibition

Reactant involved in:
  • Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents
  • Double allylic alkylation of indole-2-hydroxamates
  • SN2 substitution reactions at amide nitrogens
  • Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines
O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE Preparation Products And Raw materials
Preparation ProductsCarbamic acid, N-(1,1-dimethylethoxy)-, 1,1-dimethylethyl ester
Dimethylamine hydrochloride 1-Carboxy-1-methylethoxyammonium chloride O-Benzoyl-N-tert-butylhydroxylamine Hydrochloride 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride HYDROXYLAMINE O-Acetyl-N-tert-butylhydroxylamine Hydrochloride Cefmepidium chloride O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE 3-(2-CHLORO-PHENYL)-5-METHYL-4,5-DIHYDRO-ISOXAZOLE-5-CARBOXYLIC ACID

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