ChemicalBook Product Catalog Organic Chemistry Hydrocarbons and derivatives Hydrocarbon halides 2,6-Dichlorobenzyl bromide

2,6-Dichlorobenzyl bromide

2,6-Dichlorobenzyl bromide Basic information
Product Name:2,6-Dichlorobenzyl bromide
Synonyms:alpha-Bromo-2,6-dichlorotoluene, 2-(Bromomethyl)-1,3-dichlorobenzene;2,6-two chlorobenzyl broMide;A-BROMO-2,6-DICHLOROTOLUENE;ALPHA-BROMO-2,6-DICHLOROTOLUENE;2-(BROMOMETHYL)-1,3-DICHLOROBENZENE;2,6-DICHLOROBENZYL BROMIDE;1-BROMOMETHYL-2,6-DICHLOROBENZENE;DICHLOROBENZYL(2,6-) BROMIDE
CAS:20443-98-5
MF:C7H5BrCl2
MW:239.92
EINECS:243-827-4
Product Categories:
Mol File:20443-98-5.mol
2,6-Dichlorobenzyl bromide Structure
2,6-Dichlorobenzyl bromide Chemical Properties
Melting point 54-56 °C(lit.)
Boiling point >110°C
density 1.5832 (rough estimate)
refractive index 1.5700 (estimate)
Fp >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility methanol: 0.1 g/mL, clear
form Crystals or Crystalline Powder
color Colorless to white
BRN 637351
CAS DataBase Reference20443-98-5(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 2-(bromomethyl)-1,3-dichloro-(20443-98-5)
Safety Information
Hazard Codes C
Risk Statements 34-36/37-36
Safety Statements 22-26-27-28-36/37/39-45-25
RIDADR UN 3261 8/PG 2
WGK Germany 3
RTECS XS7966000
F 19
HazardClass 8
PackingGroup II
HS Code 29039990
MSDS Information
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2,6-Dichlorobenzyl bromide Usage And Synthesis
Chemical PropertiesWhite solid
Uses2,6-Dichlorobenzyl Bromide is used in the preparation of potent epoxide hydrolase inhibitors. Has shown thus far to relieve hypotension in lipopolysaccharide deficient murine models. As well they have been used in the synthesis of anti-HIV drugs based on diaryltriazine (DATA) analogues.
Synthesis Reference(s)Tetrahedron Letters, 29, p. 707, 1988 DOI: 10.1016/S0040-4039(00)80190-2
2,6-Dichlorobenzyl bromide Preparation Products And Raw materials
Preparation Products2-[(2,6-DICHLOROBENZYL)OXY]BENZALDEHYDE-->2-Oxazolidinone, 3-[6-[2-[(2,6-dichlorophenyl)Methoxy]ethoxy]hexyl]-5-(2,2-diMethyl-4H-1, 3-benzodioxin-6-yl)-, (5R)--->2,6-DICHLOROBENZYL METHYL ETHER-->1-(2,6-DICHLOROBENZYL)PIPERAZINE-->5-CHLORO-1-(2,6-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE
2,3,6-TRICHLOROBENZYL BROMIDE 2,6-Dichlorobenzoic acid 2-(bromomethyl)-1,3-dichloro-4-methylbenzene 2,6-Dichlorobenzonitrile Benzyltrimethylammonium chloride 2,6-Dichlorotoluene 2,6-DICHLORO-4-(TRIFLUOROMETHOXY)BENZYL BROMIDE 2,6-Dichlorobenzyl bromide 2-(bromomethyl)-1,3-dichloro-5-(methylsulfonyl)benzene 1,2-Dichloroethane Ethidium bromide Allyl bromide N,N-Dimethylbenzylamine 1,3-Dichlorobenzene Methyl bromide 1,2-Dichlorobenzene Bromotrimethylsilane Diethylstilbestrol
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