1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE

1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Basic information
Product Name:1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE
Synonyms:1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE;IBUPROFEN IMPURITY R;1,1-Bis(p-isobutylphenyl)ethane;IBuprofen Impurity 18;Ibuprofen EP Impurity R;1,1-Bis(p-isobutylphenyl)ethane(Ibuprofen EP Impurity R);Ibuprofen EP Impurity R:Ibuprofen Impurity R;1,1'-(Ethane-1,1-diyl)-4,4'-(2-meth
CAS:102120-87-6
MF:C22H30
MW:294.47
EINECS:
Product Categories:
Mol File:102120-87-6.mol
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Structure
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Chemical Properties
Boiling point 174-184 °C(Press: 2-3 Torr)
density 0.924±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Acetonitrile (Slightly), Chloroform, Methanol (Slightly)
form Oil
color Colourless
Safety Information
MSDS Information
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Usage And Synthesis
Uses1,1-Bis(p-isobutylphenyl)ethane (Ibuprofen EP Impurity R) is an impurity in the synthesis of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Preparation Products And Raw materials
Ibuprofen Ethyl Ester 2-[4-(2-Methylpropyl)phenyl] ethanol 6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one 2-(4-Methylphenyl)propanoic acid 4'-(2-Methylpropyl)acetophenone 4-(2-Methylpropyl)benzeneethanol Ibuprofen EP Impurity I 3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID p-Isobutylstyrene rac-Ibuprofen amide rac a-Hydroxy Ibuprofen (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID Ibuprofen Alcohol 2-[4-(1-METHYLPROPYL)PHENYL]PROPANOIC ACID (2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID (±)-Ibuprofen Methyl Ester trans-Ibuprofen IMpurity G M-ISOBUTYL IBUPROFEN

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