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| | Repirinast Basic information |
| Product Name: | Repirinast | | Synonyms: | 5，6-Dihydro-7，8-dimethyl-4，5-dioxo-4H-pyrano[3，2-c]quinoline-2-carboxylic acid 3-methylbutyl ester;4H-Pyrano[3,2-c]quinoline-2-carboxylic acid, 5,6-dihydro-7,8-diMethyl-4,5-dioxo-, 3-Methylbutyl Ester;Isopentyl 7,8-diMethyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-2-carboxylate;Repirinas;REPIRINAST;MY-5116;Romet;3-Methylbutyl 7,8-dimethyl-4,5-dioxo-6H-pyrano[5,6-c]quinoline-2-carboxylate | | CAS: | 73080-51-0 | | MF: | C20H21NO5 | | MW: | 355.38 | | EINECS: | | | Product Categories: | Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 73080-51-0.mol |  |
| | Repirinast Chemical Properties |
| Melting point | 236-241° | | Boiling point | 488.42°C (rough estimate) | | density | 1.2749 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO (Sparingly, Heated), Methanol (Slightly, Heated) | | form | Solid | | pka | 10.09±0.40(Predicted) | | color | White to Off-White | | Water Solubility | 1.2mg/L(temperature not stated) |
| Toxicity | LD50 in rats, mice (mg/kg): >5000 orally, >5000 s.c. both species (Nagase) |
| | Repirinast Usage And Synthesis |
| Description | Repirinast is an orally-active antiallergic agent useful in the treatment of allergic asthma.
Its activity is reportedly attributed to a metabolite, the corresponding free acid (MY-1250),
which is 17 times more potent than disodium cromoglycate in inhibiting histamine release
due to antigen-antibody reactions. | | Originator | Mitsubishi (Japan) | | Uses | Antiallergic. | | Definition | ChEBI: Repirinast is an organic molecular entity. | | Brand name | Romet |
| | Repirinast Preparation Products And Raw materials |
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