ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE

2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE

2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE Basic information
Product Name:2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE
Synonyms:ATENOLOL IMP D;ATENOLOL IMPURITY D;Atenolol IMpurity –D (EP);4-(3-Chloro-2-hydroxypropoxy)benzeneacetaMide (Atenolol IMpurity D);2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE;2-[4-[(2RS)-3-CHLORO-2-HYDROXYPROPOXY]PHENYL]ACETAMIDE;4-(3-Chloro-2-hydroxypropoxy)benzeneacetamide \n(Atenolol Impurity D);Atenolol Impurity 4（Atenolol EP Impurity D）
CAS:115538-83-5
MF:C11H14ClNO3
MW:243.69
EINECS:
Product Categories:Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:115538-83-5.mol
2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE Structure
2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE Chemical Properties
Melting point 139 - 141°C
Boiling point 492.5±40.0 °C(Predicted)
density 1.287±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
pka13.11±0.20(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE Usage And Synthesis
Uses4-(3-Chloro-2-hydroxypropoxy)benzeneacetamide is an impurity of Atenolol (A790075), a cardioselective β-adrenergic blocker. Atenolol EP Impurity D
2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE Preparation Products And Raw materials
Metoprolol Acid IMp. H (EP): 2-[4-[(2RS)-2-Hydroxy-3-[(1-Methylethyl)aMino]propoxy]phenyl]acetonitrile 2-[4-(2,3-EPOXYPROPOXY)PHENYL]ACETAMIDE 2-[4-(2,3-DIHYDROXYPROPOXY)PHENYL]ACETAMIDE 2,2'-(4,4'-(3,3'-(isopropylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy)bis(4,1-phenylene))diacetaMide 2-[4-[(2RS)-2-HYDROXY-3[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETONITRILE 4,4'-(2-HYDROXY-1,3-PROPANDIYLDIOXY)BIS(2-PHENYLACETAMIDE) 2-[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]ACETAMIDE 1-CHLORO-3-(TOLENE-P-SULPHONYLOXY) PROPANE ATENOLOL-D7 C-Desmethyl Atenolol Atenolol 4-(3-Amino-2-hydroxypropoxy)phenylacetamide 4-Hydroxyphenylacetic acid [[p-(2-methoxyethyl)phenoxy]methyl]oxirane 4-Hydroxyphenylacetamide Atenolol EP Impurity G Sodium Salt
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