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| | Thioflavine T Basic information |
| Product Name: | Thioflavine T | | Synonyms: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-benzothiazoliuchloride;Benzothiazolium,2-[4-(dimethylamino)phenyl]-3,6-dimethyl-,chloride;Thioflavine T (C.I.No.49005) for synthesis;Thioflavin T (Absorbance(E1%1cm) >=750 (410 nm to 414 nm, H2O);Thioflavin T *CAS 2390-54-7*;avin T;ThiofL;LABOTEST-BB LT00451909 | | CAS: | 2390-54-7 | | MF: | C17H19ClN2S | | MW: | 318.86 | | EINECS: | 219-228-9 | | Product Categories: | Biochemistry;Vitamin Derivatives;Vitamins | | Mol File: | 2390-54-7.mol |  |
| | Thioflavine T Chemical Properties |
| Safety Statements | 24/25 | | RIDADR | 2811 | | WGK Germany | 3 | | TSCA | Yes | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 32041300 |
| | Thioflavine T Usage And Synthesis |
| Chemical Properties | yellow to ochre-yellow powder | | Uses | Textile dyeing, fluorescent sign paints, in combination
with green or blue pigments to produce
brilliant greens, phosphotungstic pigments. | | Uses | A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease | | Definition | ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation. | | Preparation | 4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure. | | General Description | Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization. | | Biochem/physiol Actions | Cell permeable: yes | | storage | Store at -20°C | | Properties and Applications | colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.
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Standard( Silk )
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Light Fastness
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Persperation Fastness
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Ironing Fastness
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Soaping
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Fading
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Stain
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Fading
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Stain
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Fading
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Stain
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C
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3
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2-3
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4
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1
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| | Purification Methods | Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.] |
| | Thioflavine T Preparation Products And Raw materials |
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