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Alectinib Impurity

Alectinib Impurity Basic information
Product Name:Alectinib Impurity
Synonyms:Alectinib Impurity;Alectinib Impurity 11;9-Ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-8-(4-oxo-1-piperidinyl)-5H-benzo[b]carbazole-3-carbonitrile;5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-8-(4-oxo-1-piperidinyl)-
CAS:1256584-83-4
MF:C26H25N3O2
MW:411.5
EINECS:
Product Categories:
Mol File:1256584-83-4.mol
Alectinib Impurity Structure
Alectinib Impurity Chemical Properties
Boiling point 696.8±55.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
solubility Dichloromethane; Methanol
form Solid
pka13.70±0.40(Predicted)
color Pale Yellow
Safety Information
MSDS Information
Alectinib Impurity Usage And Synthesis
Uses9-Ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-8-(4-oxo-1-piperidinyl)-5H-benzo[b]carbazole-3-carbonitrile is an intermediate in synthesizing Alectinib M4 metabolite (A521150). It is the major active metabolite of Alectinib. Alectinib is an anaplastic lymphoma kinase (ALK) inhibitor and is used to treat non-?small-?cell lung cancer by blocking the activity of anaplastic lymphoma kinase (ALK).
Alectinib Impurity Preparation Products And Raw materials
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