QUAZEPAM

QUAZEPAM Basic information
Product Name:QUAZEPAM
Synonyms:Quazepam solution;dormalin;oniria;prosedar;quazepam;quazium;sch16134;QUAZEPAM CIV (200 MG)
CAS:36735-22-5
MF:C17H11ClF4N2S
MW:386.79
EINECS:253-179-4
Product Categories:
Mol File:36735-22-5.mol
QUAZEPAM Structure
QUAZEPAM Chemical Properties
Melting point 137.5-139°
Boiling point 429.9±55.0 °C(Predicted)
density 1.42±0.1 g/cm3(Predicted)
storage temp. -20°C
pka0.49±0.20(Predicted)
CAS DataBase Reference36735-22-5(CAS DataBase Reference)
NIST Chemistry ReferenceQuazepam(36735-22-5)
Safety Information
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
HS Code 2933996500
ToxicityLD50 in mice (mg/kg): >1370 i.v., >5000 orally (Orgini); LD50 in male, female mice, rats (mg/kg): 845, 921, 3072, 2749 i.p. (Black)
MSDS Information
QUAZEPAM Usage And Synthesis
DescriptionQuazepam is a rapidly acting, short term hypnotic reported to exhibit a low incidence of side effects.
OriginatorSchering (USA)
UsesQuazepam is a benzodiazepine derivative drug and is known to bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activty, motor coordination and memory. Quazepam is known to induce motor impairment and exerts hypnotic properties. Quazepam is often used for the treatment of insomina.
DefinitionChEBI: Quazepam is a benzodiazepine.
Brand nameDoral (Questcor).
General DescriptionQuazepam (Doral) and its active metabolitesreportedly are relatively selective for the benzodiazepinemodulatory site on GABAA receptors with α1 subunitand are hypnotic agents. Quazepam is metabolized by oxidation to the 2-oxo compound and then N-dealkylation.Both metabolites are active; the first reportedly is the morepotent and selective. Thereafter, 3-hydroxylation and glucuronidationoccur.
QUAZEPAM Preparation Products And Raw materials
Raw materialsDichloromethane-->1,4-Dioxane-->Chromium(VI) oxide-->Phosphorus pentasulfide-->Hexamethyleneimine-->Ruthenium tetroxide
Fenasi 2,2,2-TRIFLUOROETHYL TRICHLOROMETHANESULFONATE 7-CHLORO-5-PHENYL-2-THIOXO-2,3-DIHYDRO-1H-1,4-BENZODIAZEPINE N-(2,2,2-TRIFLUOROETHYL)BENZENAMINE HYDROCHLORIDE fletazepam QUAZEPAM Sulazepam

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.