ISOBARBITURIC ACID

ISOBARBITURIC ACID Basic information
Product Name:ISOBARBITURIC ACID
Synonyms:Fluorouracil Impurity 2(Fluorouracil EP Impurity B);Fluorouracil EP Impurity B;dihydropyrimidine-2,4,5(3H)-trione;TRIFLUOROACETIC ACID REAGENTPLUS 99%;2,4,5(3H)-Pyrimidinetrione, dihydro- (9CI);2,4,5-Trihydroxypyrimidine, 5-Hydroxyuracil;1,6-Dihydro-2,4,5(3H)-pyrimidinetrione;2-Hydroxy-1,6-dihydropyrimidine-4,5-dione
CAS:496-76-4
MF:C4H4N2O3
MW:128.09
EINECS:207-829-9
Product Categories:Nucleotides;Aromatic;PYRIMIDINE;APIs & Intermediate;Bases & Related Reagents;Heterocycles
Mol File:496-76-4.mol
ISOBARBITURIC ACID Structure
ISOBARBITURIC ACID Chemical Properties
Melting point >300 °C (dec.)(lit.)
density 1.455±0.06 g/cm3(Predicted)
solubility Soluble in DMSO (Sparingly), Methanol (Sparingly).
pka8.25±0.20(Predicted)
form crystalline
color light yellow
BRN 127205
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 2933599550
MSDS Information
ISOBARBITURIC ACID Usage And Synthesis
Chemical Propertieslight yellow to beige granular powder
UsesA 5-hydroxy derivative of the nucleobase Uracil (U801000) and an isomer of Barbituric Acid (B118650). Studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been u sed as oxidative DNA damage biomarker in tissue engineered skin
Uses2,4,5-Trihydroxypyrimidine studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin. It acts as an antagonist of uracil in the growth of Lactobacillus casei.
ISOBARBITURIC ACID Preparation Products And Raw materials
Barbituric acid Oxalic acid dihydrate 5-Methoxy-2,4-pyrimidinediol 5-fluoro-3-methyl-1H-pyrimidine-2,4-dione Chloramphenicol 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Glycine Urea 5-Chlorouracil 5-Fluorouracil Uracil 2,4,5-TRIHYDROXYPYRIMIDINE

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