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| | Apixaban Amino Acid Impurity Basic information |
| Product Name: | Apixaban Amino Acid Impurity | | Synonyms: | Apixaban impurity 12/Apixaban Amino Acid Impurity/5-((4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)amino)pentanoic acid;Apixaban
Apixaban Amino Acid Impurity;Pentanoic acid, 5-[[4-[3-(aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]-;5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid;Apixaban Open Chain Acid;Apixaban Open-ring Acid Impurity;5-((4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoic acid? (Apixaban Impurity） | | CAS: | 2206825-87-6 | | MF: | C25H27N5O5 | | MW: | 477.51 | | EINECS: | | | Product Categories: | | | Mol File: | 2206825-87-6.mol |  |
| | Apixaban Amino Acid Impurity Chemical Properties |
| Melting point | >145°C (dec.) | | Boiling point | 769.1±60.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | -20°C, Inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 4.59±0.10(Predicted) | | color | Pale Yellow to Light Yellow |
| | Apixaban Amino Acid Impurity Usage And Synthesis |
| Uses | Apixaban Open chain Acid Is an open ring impurity of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. |
| | Apixaban Amino Acid Impurity Preparation Products And Raw materials |
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