4-HYDROXY-1-METHYL-2-QUINOLONE

4-HYDROXY-1-METHYL-2-QUINOLONE Basic information

Product Name:	4-HYDROXY-1-METHYL-2-QUINOLONE
Synonyms:	AURORA KA-2363;4-HYDROXY-1-METHYL-2-QUINOLONE;4-HYDROXY-1-METHYL-1,2-DIHYDROQUINOLIN-2-ONE;4-HYDROXY-1-METHYL-1H-QUINOLIN-2-ONE;4-HYDROXY-1-METHYL-2(1H)-QUINOLONE;4-HYDROXY-N-METHYL-2-QUINOLONE;4-Hydroxy-1-methyl-2(1H)-quinolone 98%;4-hydroxy-1-methylquinolin-2-one
CAS:	1677-46-9
MF:	C10H9NO2
MW:	175.18
EINECS:	216-830-3
Product Categories:	Building Blocks;Heterocyclic Building Blocks;Intermediates of Dyes and Pigments;Quinolines
Mol File:	1677-46-9.mol

4-HYDROXY-1-METHYL-2-QUINOLONE Chemical Properties

Melting point	269-271 °C (lit.)
Boiling point	306.47°C (rough estimate)
density	1.326
refractive index	1.5060 (estimate)
pka	4.50±1.00(Predicted)
form	powder to crystal
color	Light yellow to Brown to Dark green
CAS DataBase Reference	1677-46-9(CAS DataBase Reference)
EPA Substance Registry System	2(1H)-Quinolinone, 4-hydroxy-1-methyl- (1677-46-9)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	FG7350000
Hazard Note	Irritant
HS Code	2933499090
Toxicity	mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01354,

MSDS Information

Provider	Language
SigmaAldrich	English

4-HYDROXY-1-METHYL-2-QUINOLONE Usage And Synthesis

Uses

4-Hydroxy-1-methyl-2(1H)-quinolone was used as nucleophile in electrochemical oxidation of catechols and the reaction was studied by cyclic voltammetry and controlled-potential coulometry. It was used in ceric ammonium nitrate-mediated oxidative cycloaddition of 1,3-dicarbonyls to conjugated compounds to yield substituted dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones and dihydrofurophenalenones. It was used in the synthesis of :

3-(4-methoxybenzyl)-4-hydroxy-1-methylquinolinone
3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-hydroxy-1-methylquinolin-2(1H)-one
3-(4-chlorobenzyl)-4-hydroxy-1-methylquinolin-2(1H)-one
3,3′-bis(4-chlorobenzylidene)-1,10-methylquinolin-2,20-(1H)-one

4-HYDROXY-1-METHYL-2-QUINOLONE Preparation Products And Raw materials

Raw materials

3-ACETYL-4-HYDROXY-1-METHYL-2(1H)-QUINOLINONE-->2(1H)-Quinolinone, 4-(acetyloxy)-1-methyl--->1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid-->methyl 2-(2-bromo-N-methylacetamido)benzoate-->Zinc02559774-->N-METHYLANTHRANILIC ACID-->S-(hydrogen malonyl)coenzyme A-->1,2-DIHYDRO-4-HYDROXY-1-METHYL-2-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER-->L-KYNURENINE-->N-Methylaniline-->Acetic anhydride-->L-Isoleucine

Preparation Products

Disperse Yellow 10-->DISPERSE YELLOW 5-->3-BROMO-4-(4-METHOXY-PHENYL)-1-METHYL-1H-QUINOLIN-2-ONE

AURORA KA-4095 AURORA KA-3982 AURORA KA-3897 AURORA KA-3975 AURORA KA-4044 AURORA KA-4770 AURORA KA-3186 AURORA KA-3175 AURORA KA-4139 AURORA KA-3966 AURORA KA-3983 AURORA KA-3978 AURORA KA-5559 AURORA KA-3686 4-HYDROXY-1-METHYL-2-QUINOLONE AURORA KA-3570 6-BENZYL-4-HYDROXY-2H-PYRANO[3,2-C]QUINOLINE-2,5(6H)-DIONE 4-HYDROXY-1-PHENYL-1,2-DIHYDROQUINOLIN-2-ONE

Email:[email protected] [email protected]

4-HYDROXY-1-METHYL-2-QUINOLONE

Login

Fast registration