2,4,6-Trichloropyrimidine

2,4,6-Trichloropyrimidine Basic information
Product Name:2,4,6-Trichloropyrimidine
Synonyms:2,4,6-trichloro-pyrimidin;AURORA KA-4834;2,4,6-TRICHLOROPYRIMIDINE;TCPY;Pyrimidine, 2,4,6-trichloro-;2,4,6-TRICHLOROPYRIDINE;2,3-DIHYDROIMIDAZO 2,1-BBENZO;2,4,6-Trichloropyrimidine, 98.5%
CAS:3764-01-0
MF:C4HCl3N2
MW:183.42
EINECS:223-183-0
Product Categories:Heterocycle-Pyrimidine series;Aromatics;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Organics;pharmacetical;Pyridine;Pyrimidine;Pyrimidines;PyrimidinesHeterocyclic Building Blocks
Mol File:3764-01-0.mol
2,4,6-Trichloropyrimidine Structure
2,4,6-Trichloropyrimidine Chemical Properties
Melting point 23-25 °C (lit.)
Boiling point 210-215 °C (lit.)
density 1.595 g/mL at 20 °C (lit.)
refractive index n20/D 1.57(lit.)
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
form Liquid After Melting
pka-7.14±0.30(Predicted)
color Clear colorless to yellow
Water Solubility Insoluble in water.
FreezingPoint 21.0 to 23.0 ℃
BRN 118284
InChIKeyDPVIABCMTHHTGB-UHFFFAOYSA-N
CAS DataBase Reference3764-01-0(CAS DataBase Reference)
NIST Chemistry ReferencePyrimidine, 2,4,6-trichloro-(3764-01-0)
EPA Substance Registry SystemPyrimidine, 2,4,6-trichloro- (3764-01-0)
Safety Information
Hazard Codes Xn,Xi,T
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36-24/25-23
RIDADR UN1759
WGK Germany 3
TSCA T
HazardClass 8
PackingGroup III
HS Code 29335990
MSDS Information
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2,4,6-Trichloropyrimidine English
SigmaAldrich English
ACROS English
ALFA English
2,4,6-Trichloropyrimidine Usage And Synthesis
Chemical Propertiesclear colorless to yellowish liquid after melting
UsesFungitoxic substance.
UsesIt is applied In selective Suzuki coupling with arylboronic acids has been reported to give 6-arylpyrimidines.
Synthesis Reference(s)Journal of the American Chemical Society, 80, p. 5481, 1958 DOI: 10.1021/ja01553a042
2,4,6-Trichloropyrimidine Preparation Products And Raw materials
Preparation Products4,6-DIMETHOXYPYRIMIDINE-2-SULFONYL CHLORIDE-->2,4-DIAMINO-6-FLUOROPYRIMIDINE-->2-ISOTHIOCYANATO-4,6-DIMETHOXYPYRIMIDINE-->4-AMINO-2,6-DIFLUOROPYRIMIDINE-->6-Chlorouracil-->2-AMINO-4,6-DIFLUOROPYRIMIDINE-->2,4,6-TRIMETHOXYPYRIMIDINE-->4-CHLORO-2,6-DIPHENYLPYRIMIDINE-->4-(4,6-Dichloropyrimidin-2-yl)morpholine-->4-tert-butyl-2,6-dichloropyriMidine-->4-Benzyl-2,6-dichloropyrimidine
Pyrimidine, 2,4,6-trichloro-5-ethyl- 2,4,5,6-TETRACHLOROPYRIMIDINE 5-Methyl-2,4,6-trichloropyrimidine AKOS 90001 Sulfadiazine 2,4,6-TRICHLORO-5-FLUOROPYRIMIDINE 2,4,6-TRICHLORO-5-CYANOPYRIMIDINE 2,4,6-TRICHLORO-5-(2-ACETIC ACID) PYRIMIDINE Trichloroisocyanuric acid Trichlorosilane Trichloroethylene Chloroform (2,4,6-TRICHLORO-PYRIMIDIN-5-YL)-ACETIC ACID ETHYL ESTER 2,4,6-Trichloropyrimidine 2,4,6-TRICHLOROPYRIMIDINE-5-CARBOXYLIC ACID Sucralose 2,4,6-TRICHLORO-5-NITROPYRIMIDINE Trichloroacetic acid

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