H-GLY-TYR-PRO-GLY-GLN-VAL-OH

H-GLY-TYR-PRO-GLY-GLN-VAL-OH Basic information

Product Name:	H-GLY-TYR-PRO-GLY-GLN-VAL-OH
Synonyms:	GLY-TYR-PRO-GLY-GLN-VAL;H-GLY-TYR-PRO-GLY-GLN-VAL-OH;PROTEINASE ACTIVATED RECEPTOR 4 AGONIST PEPTIDE (GYPGQV), HUMAN;PAR-4 AGONIST PEPTIDE (GYPGQV), HUMAN;PAR-4 (1-6) (HUMAN);PAR 4 (1-6);GYPGQV, Coagulation Factor II Receptor-Like 3 (1-6) (huMan), Proteinase Activated Receptor 4 (1-6) (huMan), ThroMbin Receptor-Like 3 (1-6) (huMan);Glycyl-L-tyrosyl-L-prolyl-glycyl-L-glutaminyl-L-valine trifluoroacetate salt
CAS:	225779-44-2
MF:	C28H41N7O9
MW:	619.67
EINECS:
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Mol File:	225779-44-2.mol

H-GLY-TYR-PRO-GLY-GLN-VAL-OH Chemical Properties

storage temp.	-15°C
solubility	H2O: >2mg/mL
form	powder
color	white to tan

Safety Information

WGK Germany

MSDS Information

H-GLY-TYR-PRO-GLY-GLN-VAL-OH Usage And Synthesis

Description

PAR4 (1-6) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR4 and residues 48-53 of the full-length sequence. It activates PAR4 and the cleavage site mutant PAR4^R47A when used at a concentration of 500 μM. PAR4 (1-6) induces platelet aggregation of isolated washed human platelets when used at a concentration of 1 mM but does not affect clotting time induced by factor VIIa, soluble tissue factor, and collagen in an ex vivo coagulation assay.

H-GLY-TYR-PRO-GLY-GLN-VAL-OH Preparation Products And Raw materials

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H-GLY-TYR-PRO-GLY-GLN-VAL-OH

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