3,3-Dimethylglutaric acid

3,3-Dimethylglutaric acid Basic information
Product Name:3,3-Dimethylglutaric acid
Synonyms:3,3-dimethyl-pentanedioicaci;Glutaric acid, 3,3-dimethyl-;Pentanedioic acid, 3,3-dimethyl-;3,3-DIMETHYLPENTANEDIOIC ACID;3,3-DIMETHYLPENTANEDOIC ACID;3,3-DIMETHYLGLUTARIC ACID;2,2-O-DIMETHYLPROPANE-1,3-DICARBOXYLIC ACID;2,2-DIMETHYLPROPANE-1,3-DICARBOXYLIC ACID
CAS:4839-46-7
MF:C7H12O4
MW:160.17
EINECS:225-425-0
Product Categories:Organic acids
Mol File:4839-46-7.mol
3,3-Dimethylglutaric acid Structure
3,3-Dimethylglutaric acid Chemical Properties
Melting point 100-102 °C (lit.)
Boiling point 290 °C
density 1,42 g/cm3
refractive index 1.4336 (estimate)
Fp 89-90°C/2mm
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pkapK1:3.70;pK2:6.34 (25°C)
form Fine Crystalline Powder
color White to beige
Water Solubility soluble
BRN 1765439
InChIKeyDUHQIGLHYXLKAE-UHFFFAOYSA-N
CAS DataBase Reference4839-46-7(CAS DataBase Reference)
NIST Chemistry Reference3,3-Dimethylglutaric acid(4839-46-7)
EPA Substance Registry SystemPentanedioic acid, 3,3-dimethyl- (4839-46-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA Yes
HS Code 29171990
MSDS Information
ProviderLanguage
2,2-Dimethylpropane-1,3-dicarboxylic acid English
SigmaAldrich English
ACROS English
ALFA English
3,3-Dimethylglutaric acid Usage And Synthesis
Chemical Propertieswhite to beige fine crystalline powder
UsesReactant involved in:
  • Cyclodehydration of diols
  • Synthesis of conjugates of betulin derivatives used as anti-HIV agents
  • Preparation of dimeric peptide antagonists of IgG-FcRn interaction
  • Microwave-assisted protection of glutaraldehyde
  • Synthesis of glycyrrhetinic acid derivatives for proteasome inhibition
  • Catalytic, asymmetric transannular aldolizations
Uses3,3-Dimethylglutaric Acid is a versatile reactant used in the synthesis of (+)-Hirsutene via catalytic asymmetric transannular aldolization.
Uses3,3-Dimethylglutaric acid can be used as reactant involved in: Cyclodehydration of diols; Synthesis of conjugates of betulin derivatives used as anti-HIV agents; Preparation of dimeric peptide antagonists of IgG-FcRn interaction; Microwave-assisted protection of glutaraldehyde; Synthesis of glycyrrhetinic acid derivatives for proteasome inhibition; Catalytic, asymmetric transannular aldolizations.
DefinitionChEBI: An alpha,omega-dicarboxylic acid that is glutaric acid substituted by two methyl groups at the C-3 position.
3,3-Dimethylglutaric acid Preparation Products And Raw materials
Raw materialsSodium hydroxide-->Diethyl ether-->Sodium sulfite-->Sodium hypochlorite-->Dimedone
Preparation Products2-ACETYLDIMEDONE
BIS-SILVERCYCLOHEXYL-1,1-DIACETATE 3-ETHYL-3-METHYLGLUTARIC ACID Ethyl 2-(Chlorosulfonyl)acetate BIS(1H,1H,7H-PERFLUOROHEPTYL)DICAMPHORATE TRANS-DIETHYL CARONATE (1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID Cyclopentane-1,1-diacetic acid diethyl 2,2-dimethylpentanedioate 2-METHYLPROPANE TRICARBOXYLIC ACID Ascoric Acid 1,14-DIMETHYL-4,10-DIOXATETRACYCLO[5.5.2.0(2,6).0(8,12)]TETRADEC-13-ENE-3,5,9,11-TETRAONE AURORA 2471 3-methyl-3-phenylglutaric acid β,β'-dimethylglutaric acid Cyclopropane-1,1,2,2,3,3-hexacarboxylicacidhexamethylester DIMETHYL CAMPHORATE TRIMETHYL 2,2-DIMETHYLPENTANE-1,3,5-TRICARBOXYLATE 2,3-DIMETHYLGLUTARIC ACID

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