(R)-(+)-2-Chloropropionic acid

(R)-(+)-2-Chloropropionic acid Basic information
Product Name:(R)-(+)-2-Chloropropionic acid
Synonyms:(R)-(+)-2-Chloropropionic Acid;(R)-(+)-2-Chloropropionic acid,98%;(R)-(+)-2-CHLOROPROPIONIC ACID FOR SYNTH;(R)-(+)-2-Chloropropionic acid 99%;(2R)-(+)-2-Chloropropanoic acid 98%;(2R)-(+)-2-Chloropropanoic acid;R(+)-2-Chloropropionic acid≥ 98% (Assay);(R)-2-Chloropropionic Acid,99%e.e.
CAS:7474-05-7
MF:C3H5ClO2
MW:108.52
EINECS:626-432-5
Product Categories:Synthetic Organic Chemistry;Carboxylic Acids;Miscellaneous Reagents;Carboxylic Acids (Chiral);Chiral Building Blocks;Organic Building Blocks;chiral;CHIRAL COMPOUNDS;Chiral Building Blocks
Mol File:7474-05-7.mol
(R)-(+)-2-Chloropropionic acid Structure
(R)-(+)-2-Chloropropionic acid Chemical Properties
Melting point -12°C
alpha 14 º (neat)
Boiling point 185-188 °C (lit.)
density 1.258 g/mL at 20 °C (lit.)
refractive index n20/D 1.4345(lit.)
Fp 140 °F
storage temp. −20°C
solubility soluble in Chloroform, Methanol
pka2.96±0.10(Predicted)
form clear liquid
color Colorless to Almost colorless
optical activity[α]20/D +14°, neat
BRN 1720258
CAS DataBase Reference7474-05-7(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 22-35
Safety Statements 23-26-28-36-45
RIDADR UN 2511 8/PG 3
WGK Germany 3
HazardClass 8
PackingGroup III
HS Code 29159000
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(+)-2-Chloropropionic acid Usage And Synthesis
Chemical PropertiesColourless Oil
Uses(R)-(+)-2-Chloropropionic acid can be used as a starting material in the synthesis of:???????
  • Thiolactic acid, a key intermediate, which is used for the preparation of 2(R),5(S)-oxathiolanones by reacting with pivalaldehyde.???????
  • (R)-2-chloropropionyl chloride, a key intermediate, which is utilized in the synthesis of (R)-4,5-dihydro-5-methylpyridazin-3(2H)-one derivative with pyrazolopyridine ring as a potential phosphodiesterase inhibitor.???????
  • 2-Chloropropionamide derivatives as protein disulfide isomerase (PID) inhibitors.

(R)-(+)-2-Chloropropionic acid Preparation Products And Raw materials
Raw materials2-Pentene, 4-chloro--->[R,(+)]-2-Chloropropionic acid ethyl ester-->D-Alanine
Preparation Products(S)-(-)-2-Chloropropionic acid-->(R)-(-)-2-Chloropropan-1-ol-->(S)-1-OCTYN-3-OL-->Methanol
DALAPON-METHYL ESTER (S)-2-Chloropropionic acid methyl Ethyl 2-(Chlorosulfonyl)acetate DIISOPROPYL DICHLOROMALONATE (S)-(-)-2-Chloropropionic acid Ascoric Acid b-Chloropropionic acid,3-CHLOROPROPIONIC ACID:SS-CHLOROPROPIONIC ACID (R)-(+)-2-CHLOROHEXANOIC ACID Beclomethasone dipropionate Folic acid (R)-2-CHLOROSUCCINIC ACID Clobetasol propionate (R)-(+)-2-Chloropropionic acid 2-CHLOROPROPIONIC ACID (92%),2-CHLOROPROPIONIC ACID pract,(n)-2-chloropropionic acid,(+/-)-2-CHLOROPROPIONIC ACID,A-CHLOROPROPIONIC ACID Diethyl chloromalonate Dimethyl chloromalonate phosphoric acid (R)-(+)-2-CHLOROPENTANOIC ACID

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