ChemicalBook Product Catalog API Hormones and the Endocrine System Prostaglandin drugs Carboprost

Carboprost

Carboprost Basic information
Product Name:Carboprost
Synonyms:(5z,9-alpha,11-alpha,13e,15s)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1;Carboprost Trometamol Impurity B (Carboprost);15-methylpgf2-alpha;15s)-13e;methyl-pgf2-alpha;-oicacid;prosta-5,13-dien-1-oicacid,9,11,15-trihydroxy-15-methyl-,(5z,9-alpha,11-alph;prostin15m
CAS:35700-23-3
MF:C21H36O5
MW:368.51
EINECS:
Product Categories:Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:35700-23-3.mol
Carboprost Structure
Carboprost Chemical Properties
Melting point 79-82°C
Boiling point 418.83°C (rough estimate)
density 1.0390 (rough estimate)
refractive index 1.6120 (estimate)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
pka4.76±0.10(Predicted)
form Solid
color White
CAS DataBase Reference35700-23-3(CAS DataBase Reference)
Safety Information
MSDS Information
Carboprost Usage And Synthesis
Description15(S)-15-methyl PGF2α is a metabolically stable analog of PGF2α. It is a potent uterine stimulant and abortifacient which can be administered intramuscularly to induce labor. It induces luteolysis and reduces serum progesterone concentrations when given as an intramuscular injection in non-pregnant rhesus monkeys.
Chemical PropertiesOff- White Solid
UsesAnalog of prostaglandin F2α. Oxytocic.
UsesAnalog of prostaglandin F2a. Oxytocic
DefinitionChEBI: Prostaglandin F2alpha in which the hydrogen at position 15 is substituted by methyl (S configuration). It is used as an abortifacient agent that is effective in both the first and second trimesters of regnancy.
Brand nameHemabate (Pharmacia & Upjohn).
Carboprost Preparation Products And Raw materials
Fluorescein Sodium Epoprostenol Mifepristone Carboprost methyl ester,CARBOPROST METHYLATE,CARBOPROST METHYL,METHYL CARBOPROST carboprost tromethamine,CARBOPROST TROMETHAMINE (25 MG) CARBOPROST TROMETAMOL - REFERENCE SPECTRUM CARBOPROST TROMETAMOL
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