4-Aminophenylacetic acid

4-Aminophenylacetic acid Basic information
Product Name:4-Aminophenylacetic acid
Synonyms:H-APH(4)-OH;4-AMINOPHENYLACETIC ACID;ACETIC ACID 4-AMINOPHENYL ESTER;AKOS BBS-00006880;RARECHEM AL BO 0220;Phenylglycine base;4-Aminophenylacetic;Benzeneacetic acid, 4-amino-
CAS:1197-55-3
MF:C8H9NO2
MW:151.16
EINECS:214-828-7
Product Categories:Naphthyridine,Quinoline;Others;Peptide Synthesis;Unnatural Amino Acid Derivatives;FINE Chemical & INTERMEDIATES;Aromatic Phenylacetic Acids and Derivatives;Carboxylic Acids;Phenyls & Phenyl-Het;Organic acids;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Carboxylic Acids;Phenyls & Phenyl-Het
Mol File:1197-55-3.mol
4-Aminophenylacetic acid Structure
4-Aminophenylacetic acid Chemical Properties
Melting point 201 °C (dec.) (lit.)
Boiling point 273.17°C (rough estimate)
density 1.2023 (rough estimate)
refractive index 1.5635 (rough estimate)
Fp 201°C
storage temp. Store below +30°C.
pkapK1: 3.60;pK2: 5.26 (20°C)
form Powder
color Light yellow to beige
Water Solubility Very soluble in water.
Decomposition 201 ºC
Merck 14,463
BRN 2208094
LogP0.220 (est)
CAS DataBase Reference1197-55-3(CAS DataBase Reference)
NIST Chemistry ReferenceBenzeneacetic acid, 4-amino-(1197-55-3)
EPA Substance Registry SystemBenzeneacetic acid, 4-amino- (1197-55-3)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 22-24/25-36-26
WGK Germany 3
RTECS AF3550000
13
TSCA Yes
HazardClass IRRITANT
HS Code 29224995
Toxicitymouse,LD50,intraperitoneal,3500mg/kg (3500mg/kg),Farmaco, Edizione Scientifica. Vol. 13, Pg. 286, 1958.
MSDS Information
ProviderLanguage
p-Aminophenylacetic acid English
SigmaAldrich English
ACROS English
ALFA English
4-Aminophenylacetic acid Usage And Synthesis
Chemical Propertieslight yellow to beige powder
Uses4-Aminophenylacetic acid, is used as a non-translocated competitive inhibitor of the epithelial peptide transporter PepT1. It can be detected using HPLC, NMR techniques.
UsesIt is a non-translocated competitive inhibitor of the epithelial peptide transporter PepT1
Purification MethodsCrystallise the acid from hot water (60-70mL/g). [Beilstein 14 III 1182.]
4-NITRO-1-NAPHTHALENE ACETIC ACID 2-(4-AMINOPHENYL)ACETIC ACID-1-13C 2,3-DICHLORO-6-AMINOPHENYLACETIC ACID 4-Aminophenylboronic acid ALPHA-AMINOPHENYLACETIC ACID, ISOAMYL ESTER HCL,A-AMINOPHENYLACETIC ACID ISOAMYL ESTER HYDROCHLORIDE 2-Aminophenylacetic acid Ethyl 2-(Chlorosulfonyl)acetate 2-(4-AMINOPHENYL)ACETIC ACID, TECH Ascoric Acid METHYL 4-(4-AMINOPHENYL)BUTANOATE 2-(4-NITROPHENYL)PROPIONIC ACID 4-Amino-benzenesulfonic acid monosodium salt o-Aminophenylacetic acid 4-NITROPHENYLSUCCINIC ACID 2-(AMINOPHENYL)ACETIC ACID LACTAM,O-(AMINOPHENYL)ACETIC ACID LACTAM Methyl α-methyl-p-aminophenylacetate (R)-α-Aminophenylacetic acid 3-methylbutyl ester 2'-FLUORO-(2-AMINOPHENYL)ACETIC ACID

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