Posaconazole Impurity 51

Posaconazole Impurity 51 Basic information
Product Name:Posaconazole Impurity 51
Synonyms:Posaconazole Impurity 51;4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]-1-[4-[1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,2,4-triazol-4-yl]phenyl]piperazin-2-one;Posaconazole 3-Oxo Impurity;Posaconazole Impurity 107;3-Oxo-posaconazole (3-?oxo-?1-?piperazinyl);4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazin-2-one;1-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-2-one;4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-2-one
CAS:357189-94-7
MF:C37H40F2N8O5
MW:714.7609064
EINECS:
Product Categories:
Mol File:357189-94-7.mol
Posaconazole Impurity 51 Structure
Posaconazole Impurity 51 Chemical Properties
Boiling point 911.4±75.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
pka14.72±0.20(Predicted)
Safety Information
MSDS Information
Posaconazole Impurity 51 Usage And Synthesis
Uses3-Oxo-posaconazole is an impurity of posaconazole (P689600) which is an orally active triazole antifungal.
Posaconazole Impurity 51 Preparation Products And Raw materials
Posaconazole-d5 1H-1,2,4-TRIAZOLE, 1-[[(2S)-2-(2,4-DIFLUOROPHENYL)OXIRANYL]METHYL]- 1-[1-(Bromomethyl)ethenyl]-2,4-difluoro-benzene Posaconazole DiastereoisoMer interMediate 2 Posaconazole Impurity 17 Posaconazole Impurity 44 Posaconazole Impurity 49 PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, Posaconazole-d4 Posaconazole Diastereoisomer 12 Posaconazole Impurity 25 Posaconazole Impurity 42 Posaconazole Impurity 47 D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- Posaconazole iMpurity 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one Posaconazole Diastereoisomer 13

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