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| 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Basic information |
| 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Chemical Properties |
Melting point | 231.0 to 235.0 °C | Boiling point | 521.5±60.0 °C(Predicted) | density | 1.223±0.06 g/cm3(Predicted) | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated) | pka | 7.11±0.10(Predicted) | form | Solid | color | Off-White | Water Solubility | Water: Insoluble | λmax | 287nm(CHCl3)(lit.) | Stability: | Hygroscopic | CAS DataBase Reference | 6981-18-6(CAS DataBase Reference) | EPA Substance Registry System | Ormetoprim (6981-18-6) |
Safety Statements | 24/25 | HS Code | 29333990 |
| 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Usage And Synthesis |
Uses | It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.This compound is a contaminant of emerging concern (CECs). | Definition | ChEBI: 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine is a dimethoxybenzene. | Synthesis Reference(s) | Journal of Medicinal Chemistry, 14, p. 462, 1971 DOI: 10.1021/jm00287a029 |
| 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Preparation Products And Raw materials |
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