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| | Neohesperidin Basic information |
| | Neohesperidin Chemical Properties |
| Melting point | 239-243°C | | Boiling point | 933.7±65.0 °C(Predicted) | | density | 1.65±0.1 g/cm3(Predicted) | | vapor pressure | 0Pa at 20℃ | | storage temp. | Sealed in dry,2-8°C | | solubility | DMSO (Slightly), Pyridine (Slightly) | | form | neat | | pka | 7.14±0.40(Predicted) | | color | White to Off-White | | Water Solubility | 3.98mg/L at 20℃ | | BRN | 74945 | | InChIKey | ARGKVCXINMKCAZ-RTFRIYMLSA-N | | LogP | -0.69 at 20℃ | | CAS DataBase Reference | 13241-33-3(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | DJ2981400 | | F | 10-21 | | HS Code | 29389090 |
| | Neohesperidin Usage And Synthesis |
| Description | Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities. In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL). In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo. | | Chemical Properties | White powder | | Uses | Neohesperidin can be used in cosmetic products and as a sweetening agent in food & beverages, an antioxidant flavanone glycoside
| | Uses | Neohesperidin exhibits lipid-regulating effects in vivo and in vitro. It is a main flavonoid in citrus byproducts (CBP) which possesses anti-oxidant activity. | | Definition | ChEBI: A flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. | | Flammability and Explosibility | Notclassified |
| | Neohesperidin Preparation Products And Raw materials |
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