ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Bromopyrimidine 2-Amino-5-bromopyrimidine

2-Amino-5-bromopyrimidine

2-Amino-5-bromopyrimidine Basic information
Product Name:2-Amino-5-bromopyrimidine
Synonyms:TIMTEC-BB SBB000184;5-BROMOPYRIMIDIN-2-AMINE;2-AMINO-5-BROMOPYRIMIDINE;5-BROMO-2-PYRIMIDINAMINE;5-BROMO-2-PYRIMIDINYLAMINE;5-BROMO-2-AMINOPYRIMIDINE;5-BROMOPYRIMIDIN-2-YLAMINE;2-Amino-5-Bormopyrimidine
CAS:7752-82-1
MF:C4H4BrN3
MW:174
EINECS:629-581-4
Product Categories:Bases & Related Reagents;Nucleotides;Halides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Organohalides;Pyrimidine;Aromatics Compounds;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Heterocycle-Pyrimidine series;FINE Chemical & INTERMEDIATES;Amines and Anilines;Heterocycles;Aromatics;bc0001
Mol File:7752-82-1.mol
2-Amino-5-bromopyrimidine Structure
2-Amino-5-bromopyrimidine Chemical Properties
Melting point 241-243 °C (lit.)
Boiling point 340.7±34.0 °C(Predicted)
density 1.844±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Crystalline Powder, Crystals or Flakes
pka1.93±0.10(Predicted)
color White to light beige
Water Solubility Insoluble
InChIKeyUHRHPPKWXSNZLR-UHFFFAOYSA-N
CAS DataBase Reference7752-82-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,N,Xi
Risk Statements 22-36-50/53
Safety Statements 26-60-61
RIDADR UN 3077 9/PG 3
WGK Germany 3
Hazard Note Harmful
HazardClass IRRITANT, IRRITANT-HARMFUL
PackingGroup III
HS Code 29335995
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
2-Amino-5-bromopyrimidine Usage And Synthesis
Chemical PropertiesYellow Solid
Uses2-Amino-5-bromopyrimidine was employed:
  • in synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites
  • in synthesis of 2-phthalimido-5-bromopyrimidine
  • as intermediate for the preparation of sulfanilamides and amino acids containing the pyrimidine ring system. The products are potential antiviral agents
General DescriptionCrystal structure of 2-amino-5-bromopyrimidine was studied.
SynthesisThe synthesis of 2-Amino-5-bromopyrimidine is as follows:The 2-aminopyrimidine (2.5g, 26.29mmol) was dissolved in acetonitrile (25mL) was added N- bromosuccinimide (4.6g, 27.9mmol) under ice-cooling, stirred in the dark overnight at room temperature. Recovery of the solvent under reduced pressure, washed with water (100 mL) was washed, filtered off with suction, and dried in vacuo to give a white solid. Yield: 97%.
synthesis of 8-hydroxyquinoline-N-oxide.png
storageStore in cool, well ventilated area. Keep container tightly closed. Light sensitive. Store under argon.
2-Amino-5-bromopyrimidine Preparation Products And Raw materials
Preparation Products5-BROMO-2-FLUOROPYRIMIDINE-->5-BROMO-2-(METHYLAMINO)PYRIMIDINE-->5-Pyrimidineacetic acid, 2-amino-, 1,1-dimethylethyl ester-->2-Pyrimidinamine, 5-bromo-N,N-bis[(4-methoxyphenyl)methyl]--->2,5-Dibromopyrimidine-->5-(4-Methoxyphenyl)pyrimidin-2-amine
Betaine 2-AMINO-4-METHYL-5-BROMO-6-TRIFLUOROPYRIMIDINE Acetaminophen SULFABROMOMETHAZINE (PHENYL-13C6) EC 2.6.1.2 ALTRENOGEST 2-PYRIMIDINAMINE, 5-BROMO-4-CHLORO-6-METHYL- 5-METHYLCYTOSINE 2-AMINO-5-BROMO-4-HYDROXY-6-PHENYLPYRIMIDINE Glycine 2-Aminopyrimidine 5-BROMO-2-(ISOPROPYLAMINO)PYRIMIDINE 2-Amino-5-bromopyrimidine Sulfamic acid Fluorocytosine 2-Amino-5-bromo-4,6-dimethylpyrimidine AMINO ACIDS 5-Bromopyrimidine
Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.