ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib

3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib

3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Basic information
Product Name:3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
Synonyms:3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib;Desfluoro Gefitinib;Gefitinib EP impurity B;N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine;Gefitinib Impurity 16;Gefitinib Impurity HCl (3-Deschloro-4-Desfluoro-4-Chloro-3-Fluoro Gefitinib HCl);4-Quinazolinamine, N-(4-chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;Gefitinib Impurity HCl
CAS:1603814-04-5
MF:C22H24ClFN4O3
MW:446.9
EINECS:
Product Categories:
Mol File:1603814-04-5.mol
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Structure
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Chemical Properties
Melting point 180-183oC
Boiling point 585.0±50.0 °C(Predicted)
density 1.322±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka7.00±0.10(Predicted)
form Solid
color Off-White to Light Brown
Safety Information
MSDS Information
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Usage And Synthesis
Uses3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Preparation Products And Raw materials
N-(3-Chloropropyl)morpholine O-Desmethyl Gefitinib 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 4-Defluoro-4-hydroxy Gefitinib Gefitinib N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 3-DesMorpholinyl-3-hydroxyethylaMino Gefitinib Gefitinib iMpurity 4-methoxy-3-(3-morpholinopropoxy)-2-nitrobenzonitrile 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one Gefitinib 3,4-Difluoro Impurity HCl N-(3-chloro-4-fluorophenyl)-7 -methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine 3,4-Dichloroaniline 2-aMino-4-Methoxy-5-(3-Morpholinopropoxy)benzaMide Gefitinib 3,4-difluoro iMpurity 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate 4-Methoxy-5-(3-Morpholinopropoxy)-2-nitrobenzaMide
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