Strictosidinic acid

Strictosidinic acid Basic information
Product Name:Strictosidinic acid
Synonyms:Strictosidinic acid;(2S,3R,4S)-3-Ethenyl-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-4-[[(1S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2H-pyran-5-carboxylic acid;2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[[(1S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-, (2S,3R,4S)-
CAS:150148-81-5
MF:C26H32N2O9
MW:516.54
EINECS:
Product Categories:
Mol File:150148-81-5.mol
Strictosidinic acid Structure
Strictosidinic acid Chemical Properties
Boiling point 792.8±60.0 °C(Predicted)
density 1.50±0.1 g/cm3(Predicted)
storage temp. 4°C, stored under nitrogen
pka4.67±0.70(Predicted)
Safety Information
MSDS Information
Strictosidinic acid Usage And Synthesis
Biological ActivityStrictosidinic acid, an glycosidic indole monoterpene alkaloid isolated from the leaves of Psychotria myriantha, inhibits the precursor enzymes of 5-HT biosynthesis and reduces 5-HT content. It has peripheral analgesic and antipyretic activity in mice.
in vivo

Strictosidinic acid (20 μg/μl; intra-hippocampal injection) causes a significance of 83.5% reduction in 5-HT levels. Strictosidinic acid (10 mg/kg; ip) causes a 63.4% reduction in 5- HT levels and a 67.4% reduction in DOPAC values in male Wistar rats, weighing 200-250 g.

target

5-HT Receptor

Strictosidinic acid Preparation Products And Raw materials
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Hydroxyecdysone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether beta-Sitosterol hydroxygenkwanin Cyanuric acid alpha-Terpineol beta-Eudesmol MOSLOFLAVONE alpha-Cyperone

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