ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound 4-(4-Chloro-2-thienyl)-2-thiazolamine

4-(4-Chloro-2-thienyl)-2-thiazolamine

4-(4-Chloro-2-thienyl)-2-thiazolamine Basic information
Product Name:4-(4-Chloro-2-thienyl)-2-thiazolamine
Synonyms:2-ThiazolaMine, 4-(4-chloro-2-thienyl)-;2-ThiazolaMine, 4-(4-chloro-2-thienyl)- 2-ThiazolaMine, 4-(4-chloro-2-thienyl)-;4-(4-Chloro-2-thienyl)-2-thiazolamine;2-Amino-4-(4-chlorothiophen-2-yl)thiazole;4-(4-chlorothiophen-2-yl)-1,3-thiazol-2-amine;4-(4-Chlorothiophen-2-yl)thiazol-2-amine;Avatrombopag Impurity 8;2-ThiazolaMine, 4-(4-chloro-2-thienyl)- 2-ThiazolaMine
CAS:570407-10-2
MF:C7H5ClN2S2
MW:216.71
EINECS:1312995-182-4
Product Categories:
Mol File:570407-10-2.mol
4-(4-Chloro-2-thienyl)-2-thiazolamine Structure
4-(4-Chloro-2-thienyl)-2-thiazolamine Chemical Properties
Boiling point 395.3±27.0 °C(Predicted)
density 1.535±0.06 g/cm3(Predicted)
pka3.47±0.10(Predicted)
Safety Information
MSDS Information
4-(4-Chloro-2-thienyl)-2-thiazolamine Usage And Synthesis
Uses4-(4-Chloro-2-thienyl)-2-thiazolamine can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
SynthesisSynthesis_570407-10-2
Bromine was added to an ether solution of 4-chloro-2-acetylthiophene under ice cooling, and the mixture was stirred at room temperature for 2 hours to obtain a brominated compound. Thiourea was added to an EtOH solution of the brominated compound at room temperature, and the mixture was stirred overnight at 80??C to obtain 2-amino-4-(4-chlorothiophen-2-yl)thiazole.
4-(4-Chloro-2-thienyl)-2-thiazolamine Preparation Products And Raw materials
Raw materials677007-73-7-->2-ACETYL-4-CHLOROTHIOPHENE-->Carbamimidothioic acid
Preparation ProductsAvatrombopag
3,4-DIHYDROXYPHENYLACETONE Vildagliptin Impurity 10 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Carbidopa Impurity 2 1-Cyclohexylpiperazine 2-Bromo (S)-Carbidopa Apixaban Impurity 17 4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine Carbidopa methyl ester, hydrochloride 5-bromo-4-(4-chlorothiophen-2-yl)thiazol-2-amine N-[(4-Fluorophenyl)methyl]-1-methyl-4-piperidinamine Methyldopa 4-(2-Methylpropoxy)benzenemethanamine acetate (1:1) Avatrombopag Impurity 49 Avatrombopag Impurity 77 2-CHLORO-1-(4,5-DICHLORO-2-THIENYL)ETHAN-1-ONE Carbidopa Monohydrate Flurbiprofen Impurity 5
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