ChemicalBook Product Catalog Pharmaceutical intermediates Bulk Drug Intermediates tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Basic information
Physical Form
Product Name:tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
Synonyms:1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE;OTAVA-BB 1207229;4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester;1-Piperazinecarboxylic acid, 4-(6-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester;tert-butyl 4-(6-aMinopyri;4-(6-aMinopyridin-3-yl)piperazine-1-carboxylic;PALBOCICLIB4;2-Methyl-2-propanyl 4-(6-amino-3-pyridinyl)-1-piperazinecarboxylate
CAS:571188-59-5
MF:C14H22N4O2
MW:278.35
EINECS:695-268-4
Product Categories:PD 0332991;Palbociclib;Anticancer;571188-59-5
Mol File:571188-59-5.mol
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Structure
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Chemical Properties
Melting point 130-132℃
Boiling point 454.1±45.0 °C(Predicted)
density 1.182
vapor pressure 0-0Pa at 20-25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Very Slightly)
form Solid
pka7.36±0.26(Predicted)
color Dark Yellow
Sensitive Air Sensitive
InChIInChI=1S/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)11-4-5-12(15)16-10-11/h4-5,10H,6-9H2,1-3H3,(H2,15,16)
InChIKeyRMULRXHUNOVPEI-UHFFFAOYSA-N
SMILESN1(C(OC(C)(C)C)=O)CCN(C2=CC=C(N)N=C2)CC1
LogP1.6-1.8 at 35℃ and pH7-9
Safety Information
HS Code 2933599590
MSDS Information
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Usage And Synthesis
Physical FormSolid
Uses4-(6-Amino-3-pyridyl)-1-Boc-piperazine is used as an organic chemical synthesis intermediate.
7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl- Cholan-24-oic acid,6-ethyl-3-hydroxy-7-oxo-,(3α,5β,6β)- 1-N-BOC-4-BROMOPIPERIDINE N-Boc-piperidine-4-aldehyde PD 0332991 HCl 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Palbociclib 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril Copper(II) chloride dihydrate LEE011 (hydrochloride) 1,4-BenzenediaMine, N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]-2-nitro- LEE011 (succinate) 1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl ester 5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione Iodomethane
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