4',7-Dimethoxyisoflavone

4',7-Dimethoxyisoflavone Basic information
Product Name:4',7-Dimethoxyisoflavone
Synonyms:7,4'-DIMETHOXYISOFLAVONE;4',7-DIMETHOXYISOFLAVONE;4',7-DIMETHOXYISOFLAVONE DIMETHYL ETHER;DAIDZEIN DIMETHYL ETHER;DIMETHOXYISOFLAVONE,4',7-;7-methoxy-3-(4-methoxyphenyl)chromen-4-one;7-methoxy-3-(4-methoxyphenyl)chromone;7-methoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one
CAS:1157-39-7
MF:C17H14O4
MW:282.29
EINECS:
Product Categories:Iso-Flavones
Mol File:1157-39-7.mol
4',7-Dimethoxyisoflavone Structure
4',7-Dimethoxyisoflavone Chemical Properties
Melting point 161-163°C
Boiling point 452.8±45.0 °C(Predicted)
density 1.242±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in DMSO
λmax260nm(MeOH)(lit.)
BRN 265550
LogP3.430 (est)
CAS DataBase Reference1157-39-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
10
HS Code 2932.99.7000
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
4',7-Dimethoxyisoflavone Usage And Synthesis
Chemical PropertiesYellow crystal, soluble in methanol, ethanol, DMSO and other organic solvents.
Uses4',7-Dimethoxyisoflavone is a flavonoid compound. It is isolated from the leaves of Albizzia lebbeck, which shows antifungal activity. It has been shown to inhibit the proliferation of cancer cells in vitro. It also inhibits the activity of a-ring hydroxylase and epoxide hydrolase. The optimum concentration for 4',7-dimethoxyisoflavone is 10 μM. This chemical is metabolized by cytochrome P450 enzymes, with bosentan as an inhibitor. Bosentan also inhibits the formation rate of 4',7-dimethoxyisoflavone by hydrogen bonding with this chemical in vitro.
Biological Activity4', 7-Dimethoxyisoflavone is a flavonoid isolated from Albizia laparvais with antifungal effect.
in vitro4',7-Dimethoxyisoflavone shows antifungal activity against some plant pathogenic fungi tested in vitro, and the sensitivity of different fungi to this chemical varied considerably.
target

Human Endogenous Metabolite

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4',7-Dimethoxyisoflavone Preparation Products And Raw materials
Dacthal Diphenyldimethoxysilane 2,6-Dimethoxybenzaldehyde N,N-Dimethylformamide Dimethyldimethoxysilane ETHANE 4',7-Dimethoxyisoflavone Dimethyl fumarate 1,1-Dimethoxyethane Daidzein Dimethyl sulfoxide Dimethyl disulfide 4',6,7-Trimethoxyisoflavone Dimethyl ether Dimethyl carbonate 4H-1-Benzopyran-4-one, 3-(3,4-dimethoxyphenyl)-7-methoxy- Dimethoxymethane Dimethyl sulfate

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