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| | Diethylacetamide Basic information |
| Product Name: | Diethylacetamide | | Synonyms: | n,n-diaethylacetamid;n,n-diethyl-acetamid;diethylacetamide;ACETIC ACID DIETHYLAMIDE;ACETYL DIETHYLAMINE;N-ACETYLDIETHYLAMINE;N,N-DIETHYLACETAMIDE;N,N-Diethylacetamide,99% | | CAS: | 685-91-6 | | MF: | C6H13NO | | MW: | 115.17 | | EINECS: | 211-685-2 | | Product Categories: | | | Mol File: | 685-91-6.mol |  |
| | Diethylacetamide Chemical Properties |
| Melting point | <20 °C | | Boiling point | 182-186 °C (lit.) | | density | 0.925 g/mL at 25 °C (lit.) | | vapor pressure | 1.2 hPa (25 °C) | | refractive index | n20/D 1.440(lit.) | | Fp | 159 °F | | storage temp. | Store below +30°C. | | solubility | 53.5g/l | | pka | -0.41±0.70(Predicted) | | form | clear liquid | | color | Colorless to Almost colorless | | Water Solubility | Soluble in water. | | BRN | 1209428 | | CAS DataBase Reference | 685-91-6(CAS DataBase Reference) | | NIST Chemistry Reference | Acetamide, N,N-diethyl-(685-91-6) | | EPA Substance Registry System | N,N-Diethylacetamide (685-91-6) |
| | Diethylacetamide Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | N,N-Diethylacetamide was used to investigate the spectroscopic properties ofN,N-diethyl-2-[(4-substituted)phenylsulfinyl] acetamides. It is commonly used as drug solvent. | | Synthesis Reference(s) | Chemistry Letters, 18, p. 1983, 1989
The Journal of Organic Chemistry, 59, p. 4035, 1994 DOI: 10.1021/jo00094a004 | | General Description | N,N-Diethylacetamide is commonly used as drug solvent. | | Hazard | Toxic by ingestion. | | Safety Profile | Moderately toxic by
ingestion and intraperitoneal routes.
Questionable carcinogen with experimental
tumorigenic data. Flammable when exposed
to heat or flame. To fight fire, use foam,
mist, CO2, dry chemical. When heated to
decomposition it emits toxic fumes of NOx. | | Purification Methods | Dissolve the amide in cyclohexane, shake with anhydrous BaO and then filter. The procedure is repeated three times, and the cyclohexane is distilled off at atmospheric pressure. The crude amide is also fractionally distilled three times from anhydrous BaO. [Beilstein 4 III 349.] |
| | Diethylacetamide Preparation Products And Raw materials |
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