LYSERGOL

LYSERGOL Basic information
Description Source
Product Name:LYSERGOL
Synonyms:10-didehydro-6-methyl-(8-beta)-ergoline-8-methano;9,10-didehydro-6-methyl-8-hydroxymethylergoline;9,10-didehydro-8-hydroxymethyl-6-methyl-ergolin;LYSERGOL;(5β)-9,10-Didehydro-6-methylergoline-8β-methanol;9,10-Didehydro-6-methylergoline-8β-methanol;Lysergole;Lysergol,97%
CAS:602-85-7
MF:C16H18N2O
MW:254.33
EINECS:210-024-5
Product Categories:Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:602-85-7.mol
LYSERGOL Structure
LYSERGOL Chemical Properties
Melting point 248°C
Boiling point 397.54°C (rough estimate)
density 1.0398 (rough estimate)
refractive index 1.6240 (estimate)
storage temp. Store at -20°C
solubility DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka14.61±0.10(Predicted)
form Solid
color Pale Brown to Light Brown
InChIInChI=1/C16H18N2O/c1-18-8-10(9-19)5-13-12-3-2-4-14-16(12)11(7-17-14)6-15(13)18/h2-5,7,10,15,17,19H,6,8-9H2,1H3/t10-,15-/s3
InChIKeyBIXJFIJYBLJTMK-HFQWXNFCNA-N
SMILESCN1C[C@H](CO)C=C2C3=CC=CC4NC=C(C3=4)C[C@@]12[H] |&1:3,18,r|
LogP1.760 (est)
Safety Information
Hazard Codes T+,T
Risk Statements 26/27/28-36/37/38-25
Safety Statements 26-36/37/39-45-36/37
RIDADR 1544
HazardClass 6.1(a)
PackingGroup II
MSDS Information
LYSERGOL Usage And Synthesis
DescriptionLysergol is an alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi (most within Claviceps), and in the morning glory family of plants (Convolvulaceae), including the hallucinogenic seeds of Rivea corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian baby woodrose) and Ipomoea violacea. Lysergol is not a controlled substance in the USA. Its possession and sale is also legal under the U.S. Federal Analog Act because it does not have a known pharmacological action or a precursor relationship to LSD, which is a controlled substance. However, lysergol is an intermediate in the manufacture of some ergoloid medicines (e.g., nicergoline).
SourceIpomoea muricata synonyms I. turbinate, Calonyction muricata belongs to the family of the Convolvulaceae. It is a creeper and widely grows in all places. The plant is commonly known as morning glory. Flowers are purple or white up to 8 cm diameter. Fruits are pendulum shape capsules. Seeds are commonly known as “Kaladana” in trade and are being used as purgative in India and Pakistan.
Chemical Propertiesoff-white to beige crystalline powder
UsesLysergol is an ergot alkaloid which when used in combination with antibiotic nalidixic acid, can effectively inhibit Escherichia coli. It also maintains the potential to act on the 5-HT1/2 receptors and at α1-adrenergic receptors thus acting as a neuropsychiatric drug.
DefinitionChEBI: An alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi and in the morning glory family of plants. Its structure is that of ergoline with a methyl group at N-6 and a beta-hydroxymethyl substituent at -8.
LYSERGOL Preparation Products And Raw materials
Preparation Products10-methoxy-1,6-dimethylergoline-8beta-methanol
3-(2-Methylaminoethyl)indole 3-[2-(ETHYLAMINO)ETHYL]INDOLE 3-(ISOPROPYLAMINO)-PROPAN-1-OL 4-Methylindole 1H-INDOLE-4-ETHANAMINE 3-BUTEN-1-AMINE (-)-2-[METHYLAMINO]-1-PHENYLPROPANE 3-(2-AMINOPROPYL)INDOLE N-Ethylmethallylamine 3-HEPTEN-1-OL 4-METHYL-3-PENTEN-1-OL (8-beta)-9,10-Didehydro-1,6-dimethyl-8-(methoxymethyl)ergoline 3-(dimethylamino)-2-methylpropan-1-ol N-isobutyl-N-isopropylamine 2-METHYL-3-BUTEN-1-OL N,N-Dimethyltryptamine CHEMBRDG-BB 4024896 2-PHENYL-1-PENTENE

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