2,6-Difluoropyridine

2,6-Difluoropyridine Basic information
Product Name:2,6-Difluoropyridine
Synonyms:2,6-Difluoropyridine, 99% 5GR;2,6- twofluorine pyridine;2,6-Difluoropyridine, 97+%;2, 6-2 fluoride pyridine;2,6-difluoropyridi;2,6-Difluorpyridin;2,6-DifL;2,6-DIFLUOROPYRIDINE
CAS:1513-65-1
MF:C5H3F2N
MW:115.08
EINECS:216-152-8
Product Categories:Fluorine series;Building Blocks;Chemical Synthesis;Fluorinated Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Fluorin-contained pyridine series;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine;Pyridines;Fluoropyridines;C5;Heterocyclic Building Blocks;Other Fluorinated Heterocycles;Halopyridines;bc0001
Mol File:1513-65-1.mol
2,6-Difluoropyridine Structure
2,6-Difluoropyridine Chemical Properties
Boiling point 124.5 °C/743 mmHg (lit.)
density 1.268 g/mL at 25 °C (lit.)
refractive index n20/D 1.437(lit.)
Fp 93 °F
storage temp. Inert atmosphere,2-8°C
solubility Not miscible or difficult to mix.
form Liquid
pka-6.09±0.10(Predicted)
Specific Gravity1.268
color Clear purple-red
BRN 1422549
InChIKeyMBTGBRYMJKYYOE-UHFFFAOYSA-N
CAS DataBase Reference1513-65-1(CAS DataBase Reference)
NIST Chemistry Reference2,6-Difluoropyridine(1513-65-1)
Safety Information
Hazard Codes Xi,T,F
Risk Statements 10-36/37/38
Safety Statements 16-26-36/37/39-37/39
RIDADR UN 1993 3/PG 3
WGK Germany 3
10
Hazard Note Toxic
HazardClass 3
PackingGroup III
HS Code 29333999
MSDS Information
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2,6-Difluoropyridine Usage And Synthesis
Chemical PropertiesColorless to light yellow liquid
Uses2,6-Difluoropyridine has been used in the preparation of poly(pyridine ether)s via polycondensation with silylated 1,1,1-tris(4-hydroxyphenyl)ethane.
General DescriptionLithium diisopropylamide (LDA)-mediated ortholithiations of 2,6-difluoropyridine in tetrahydrofuran at -78°C has been studied using a combination of IR and NMR spectroscopic and computational methods. Polycondensation of bistrimethylsilyl derivatives of various diphenols with 2,6-difluoropyridine in N-methylpyrrolidone in the presence of K2CO3 has been investigated.
3,5-Dichloro-2,4,6-trifluoropyridine 3,5-Dichloro-4-amino-2,6-difluoropyridine,4-AMINO-3,5-DICHLORO-2,6-DIFLUOROPYRIDINE 2-Chloro-5-chloromethylpyridine DIPIPERIDINOMETHANE 2,3,5,6-TETRAFLUORO-4-HYDRAZINOPYRIDINE 3,5-DIFLUOROPYRIDINE Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE 2,5-DIFLUOROPYRIDINE 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE 2,5-PYRIDINEDICARBOXYLIC ACID 2,6-Difluoropyridine Flupirtine 2,6-Lutidine 2,3,5,6-TETRAFLUORO-4-PYRIDINOL 2,5-Dimethylpyridine 2,4-DIFLUORO-PYRIDINE 2,3-DIFLUOROPYRIDINE

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