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| (+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE Basic information |
| (+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE Chemical Properties |
Boiling point | 520.6±50.0 °C(Predicted) | density | 1.433±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,2-8°C | solubility | DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:10): 100 μg/ml; DMSO: 17 mg/ml; Ethanol: 20 mg/ml | form | A crystalline solid | pka | 13.34±0.20(Predicted) |
| (+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE Usage And Synthesis |
Uses | (3aR,?4R,?5R,?6aS)?-Hexahydro-?5-?hydroxy-?4-?[(1E,?3R)?-?3-?hydroxy-?4-?[3-?(trifluoromethyl)?phenoxy]?-?1-?buten-?1-?yl]?-?2H-?cyclopenta[b]?furan-?2-?one is involved in the preparation of prostaglandin derivatives. |
| (+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE Preparation Products And Raw materials |
Raw materials | [1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-4-formylhexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl ester-->(-)-Corey lactone 4-phenylbenzoate alcohol-->[1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2H-cyclopenta[b]furan-5-yl ester-->3-Trifluoromethylphenol-->[1,1'-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-hexahydro-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl ester-->Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate-->Methyl-3-trifluoromethylphenoxyacetate, 98 % |
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