N-CARBAMYL-L-GLUTAMIC ACID

N-CARBAMYL-L-GLUTAMIC ACID Basic information
Product Name:N-CARBAMYL-L-GLUTAMIC ACID
Synonyms:N-CARBAMYL-L-GLUTAMIC ACID;carbamino-l-glutamicacid;carbamylglutamicacid;NCG,N-carbamyl-L-glutamic acid;N-(Aminocarbonyl)-L-Glutamic Acid(Carglumic Acid);N-Carbamyl-L-glutamate;N-Cbm-Glu-OH;N-Carbamyl-L-glutamic
CAS:1188-38-1
MF:C6H10N2O5
MW:190.15
EINECS:601-569-3
Product Categories:CARBAGLU;A - H;Amino Acids;Modified Amino Acids
Mol File:1188-38-1.mol
N-CARBAMYL-L-GLUTAMIC ACID Structure
N-CARBAMYL-L-GLUTAMIC ACID Chemical Properties
Melting point 174°
Boiling point 438.1±45.0 °C(Predicted)
density 1.499±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka3.71±0.10(Predicted)
color White to Off-White
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37
WGK Germany 3
RTECS LZ9870000
HS Code 2924190002
MSDS Information
ProviderLanguage
SigmaAldrich English
N-CARBAMYL-L-GLUTAMIC ACID Usage And Synthesis
Usescarbamylphosphate synthetase activator
UsesN-Carbamyl-L-glutamic Acid has been shown to have protective effects against ammonia intoxication and is used in the treatment of acute hyperammonemia.
DefinitionChEBI: A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.
N-CARBAMYL-L-GLUTAMIC ACID Preparation Products And Raw materials
Raw materials3-UREIDOPROPIONIC ACID-->Sodium cyanate-->Urea-->L-Glutamic acid-->Potassium cyanate
L-GLUTAMATE OXIDASE Phenibut 4-Ethoxy-N,N,N-trimethyl-4-oxo-1-butanaminium chloride Guanidineacetic acid CARBAMOYL-DL-ALA-OH HYDANTOIC ACID N-CARBAMYL-L-GLUTAMIC ACID N-CARBAMYL-DL-ALPHA-AMINO-N-BUTYRIC ACID 4-UREIDO-BUTYRIC ACID N-[[[(1S)-1-CARBOXY-3-METHYLBUTYL]AMINO]CARBONYL]-L-GLUTAMIC ACID

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