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| | Fmoc-S-Trityl-L-penicillamine Basic information |
| Product Name: | Fmoc-S-Trityl-L-penicillamine | | Synonyms: | FMOC-PENICILLAMINE(TRT)-OH;FMOC-S-TRITYL-BETA,BETA-DIMETHYL-L-CYS-OH;FMOC-S-TRITYL-L-PENICILLAMINE;FMOC-CYSME 2(TRT)-OH;FMOC-BETA,BETA-DIMETHYL-CYS(TRT)-OH;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-3,3-DIMETHYL-L-CYSTEINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-PENICILLAMINE;N-ALPHA-FMOC-S-TRITYL-L-PENICILLAMINE | | CAS: | 201531-88-6 | | MF: | C39H35NO4S | | MW: | 613.76 | | EINECS: | | | Product Categories: | Unusual Amino Acids;Fmoc-Amino acid series | | Mol File: | 201531-88-6.mol |  |
| | Fmoc-S-Trityl-L-penicillamine Chemical Properties |
| Boiling point | 768.8±60.0 °C(Predicted) | | alpha | 33 º (c=1 in methanol) | | density | 1.242±0.06 g/cm3(Predicted) | | storage temp. | Store at -15°C to -25°C. | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 3.70±0.10(Predicted) | | optical activity | [α]/D +33±2°, c = 1 in methanol | | InChIKey | XSGMGAINOILNJR-PGUFJCEWSA-N | | SMILES | C(O)(=O)[C@H](C(SC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O | | CAS DataBase Reference | 201531-88-6(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 2930 90 16 | | HazardClass | IRRITANT |
| | Fmoc-S-Trityl-L-penicillamine Usage And Synthesis |
| Description | Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation. | | Chemical Properties | White to off-white powder | | Uses | Fmoc-s-trityl-l-penicillamine is a new peptidomimetic furin inhibitors with potent anti-infectious activity. |
| | Fmoc-S-Trityl-L-penicillamine Preparation Products And Raw materials |
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